Arai M, Wada N, Maruyama K, Nomiyama T, Tanaka S, Okazaki I
Department of Community Health, School of Medicine, Tokai University, Kanagawa, Japan.
J Gastroenterol. 1995 Aug;30(4):539-42. doi: 10.1007/BF02347575.
We report a case of acute hepatitis in a 28-year-old male with acquired rubella infection. Serological tests revealed acute rubella virus infection and ruled out infection by other common viruses, including type A and type B hepatitis viruses. The patient showed not only marked increase of lactate dehydrogenase (LDH) activity, with only slight liver dysfunction, but also platelet and kidney injury, suggesting systemic rubella virus infection. Because the liver dysfunction was slight, liver biopsy was not performed. When a patient has mild, transient hepatitis accompanied by high LDH activity in comparison with both aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels, we should take a common viral infection such as rubella into consideration when making a diagnosis.
我们报告一例28岁男性因获得性风疹感染导致急性肝炎的病例。血清学检测显示为急性风疹病毒感染，并排除了包括甲型和乙型肝炎病毒在内的其他常见病毒感染。该患者不仅乳酸脱氢酶（LDH）活性显著升高，肝功能仅有轻微异常，还出现了血小板和肾脏损伤，提示风疹病毒全身性感染。由于肝功能异常轻微，未进行肝活检。当患者出现轻度、短暂性肝炎，且与天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）水平相比LDH活性较高时，我们在诊断时应考虑风疹等常见病毒感染。
