Alballa S R
Department of Medicine, College of Medicine, Riyadh, Saudi Arabia.
Clin Rheumatol. 1995 May;14(3):342-6. doi: 10.1007/BF02208351.
Eighty-seven patients with systemic lupus erythematosus (SLE) were retrospectively studied in King Khalid University Hospital, Riyadh. There were 78 females and 9 males (F:M ratio of 9:1). The mean age (+/- SD) at onset and at diagnosis were 25.3 +/- 10.5 and 28.5 +/- 10.9 years, respectively, with peak incidence in the 20-30 year age group. Musculoskeletal (91%), constitutional (76%), cutaneous (72%) and renal (63%) manifestations occurred most frequently, while neuropsychiatric manifestations (26%), photosensitivity (26%) and oral ulcers (16%) were relatively less frequent. The most common laboratory abnormalities included ANA (98%), anti-DNA (93%), LE cells (66%) and lymphopenia (70%). There were seven deaths during the study period and most of them were related to renal failure and complications from infections. Overall, the pattern of SLE observed in the series was comparable to that observed in other series among Caucasians.
在利雅得的哈立德国王大学医院对87例系统性红斑狼疮（SLE）患者进行了回顾性研究。其中有78名女性和9名男性（女性与男性比例为9:1）。发病时和诊断时的平均年龄（±标准差）分别为25.3±10.5岁和28.5±10.9岁，发病高峰在20 - 30岁年龄组。肌肉骨骼表现（91%）、全身症状（76%）、皮肤表现（72%）和肾脏表现（63%）最为常见，而神经精神表现（26%）、光敏性（26%）和口腔溃疡（16%）相对较少见。最常见的实验室异常包括抗核抗体（ANA，98%）、抗双链DNA抗体（93%）、狼疮细胞（66%）和淋巴细胞减少（70%）。研究期间有7例死亡，其中大多数与肾衰竭和感染并发症有关。总体而言，该系列中观察到的SLE模式与其他白种人系列中观察到的模式相当。
