通过新型补体结合试验诊断美洲锥虫病（恰加斯病）。
Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test.
作者信息
Garcia E, Ramirez L E, Monteon V, Sotelo J
机构信息
National Institute of Neurology and Neurosurgery of Mexico, Mexico City.
出版信息
J Clin Microbiol. 1995 Apr;33(4):1034-5. doi: 10.1128/jcm.33.4.1034-1035.1995.
Abstract
A new immunodiagnostic method of complement fixation was used for serodiagnosis of American trypanosomiasis; 92% sensitivity and 99% specificity were obtained, for an overall accuracy of 97%. This test can be used in field studies, obviating the use of most laboratory equipment and imported reagents; places where economic limitations hinder the use of other immunodiagnostic procedures; and in association with other tests for confirmation of the diagnosis.
摘要
一种新的补体结合免疫诊断方法被用于美洲锥虫病的血清学诊断；获得了92%的灵敏度和99%的特异性，总体准确率为97%。该检测可用于现场研究，无需使用大多数实验室设备和进口试剂；适用于经济条件限制妨碍使用其他免疫诊断方法的地方；还可与其他检测联合使用以确诊。
相似文献
1
Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test.通过新型补体结合试验诊断美洲锥虫病（恰加斯病）。
J Clin Microbiol. 1995 Apr;33(4):1034-5. doi: 10.1128/jcm.33.4.1034-1035.1995.
2
[The evaluation of a new complement fixation microtechnic (Garcia & Sotelo, 1991) for the diagnosis of chronic Chagas disease with different antigenic preparations].[用不同抗原制剂评估一种用于诊断慢性恰加斯病的新型补体结合微量技术（加西亚和索特洛，1991年）]
Rev Soc Bras Med Trop. 1997 Nov-Dec;30(6):493-9. doi: 10.1590/s0037-86821997000600009.
3
High resolution of Trypanosoma cruzi amastigote antigen in serodiagnosis of different clinical forms of Chagas' disease.克氏锥虫无鞭毛体抗原在恰加斯病不同临床类型血清诊断中的高分辨率研究
J Clin Microbiol. 1993 Jun;31(6):1486-92. doi: 10.1128/jcm.31.6.1486-1492.1993.
4
Serodiagnosis of chronic and acute Chagas' disease with Trypanosoma cruzi recombinant proteins: results of a collaborative study in six Latin American countries.利用克氏锥虫重组蛋白对慢性和急性恰加斯病进行血清学诊断：六个拉丁美洲国家合作研究的结果
J Clin Microbiol. 2004 Jan;42(1):449-52. doi: 10.1128/JCM.42.1.449-452.2004.
5
High specificity of Trypanosoma cruzi epimastigote ribonucleoprotein as antigen in serodiagnosis of Chagas' disease.克氏锥虫前鞭毛体核糖核蛋白作为抗原在恰加斯病血清诊断中的高特异性。
J Clin Microbiol. 1995 Jun;33(6):1456-60. doi: 10.1128/jcm.33.6.1456-1460.1995.
6
A rapid slide flocculation test for the diagnosis of American trypanosomiasis using Trypanosoma cruzi fragments preserved by lyophilization. Comparison with hemagglutination, immunofluorescence, and complement fixation tests.一种使用冻干保存的克氏锥虫片段诊断美洲锥虫病的快速玻片絮凝试验。与血凝试验、免疫荧光试验和补体结合试验的比较。
Am J Trop Med Hyg. 1975 Jul;24(4):586-9. doi: 10.4269/ajtmh.1975.24.586.
7
Purified excreted-secreted antigens from Trypanosoma cruzi trypomastigotes as tools for diagnosis of Chagas' disease.从克氏锥虫锥鞭毛体中纯化的排泄-分泌抗原作为恰加斯病诊断工具。
J Clin Microbiol. 2006 Feb;44(2):291-6. doi: 10.1128/JCM.44.2.291-296.2006.
8
[Complement fixation test for Chagas' disease with active serum: its importance for blood banks].[用活性血清进行恰加斯病补体结合试验：其对血库的重要性]
Rev Paul Med. 1980 Jul-Aug;96(1-2):33-6.
9
Recombinant Trypanosoma cruzi antigens and Chagas' disease diagnosis: analysis of a workshop.重组克氏锥虫抗原与恰加斯病诊断：一次研讨会分析
FEMS Microbiol Immunol. 1991 Dec;4(1):11-9. doi: 10.1111/j.1574-6968.1991.tb04965.x.
10
Serodiagnosis of American trypanosomosis by using nonpathogenic trypanosomatid antigen.使用非致病性锥虫抗原进行美洲锥虫病的血清学诊断。
J Clin Microbiol. 1997 Dec;35(12):3316-9. doi: 10.1128/jcm.35.12.3316-3319.1997.
引用本文的文献
1
Accuracy of Diagnostic Tests for the Detection of Chagas Disease: A Systematic Review and Meta-Analysis.用于检测恰加斯病的诊断测试的准确性：一项系统评价和荟萃分析。
Diagnostics (Basel). 2022 Nov 10;12(11):2752. doi: 10.3390/diagnostics12112752.
本文引用的文献
1
American trypanosomiasis (Chagas' disease)--a tropical disease now in the United States.美洲锥虫病（恰加斯病）——一种如今在美国出现的热带疾病。
N Engl J Med. 1993 Aug 26;329(9):639-44. doi: 10.1056/NEJM199308263290909.
2
Chagas' disease diagnosis: evaluation of several tests in blood bank screening.恰加斯病诊断：血库筛查中多种检测方法的评估
Transfusion. 1993 Oct;33(10):830-4. doi: 10.1046/j.1537-2995.1993.331094054620.x.
3
Increased specificity of serodiagnosis of Chagas' disease by detection of antibody to the 72- and 90-kilodalton glycoproteins of Trypanosoma cruzi.
J Infect Dis. 1987 Mar;155(3):561-4. doi: 10.1093/infdis/155.3.561.
4
A new complement fixation test for the diagnosis of neurocysticercosis in cerebrospinal fluid.
J Neurol. 1991 Oct;238(7):379-82. doi: 10.1007/BF00319856.
5
Prevalence of antibody to Trypanosoma cruzi among blood donors in Los Angeles, California.加利福尼亚州洛杉矶市献血者中克氏锥虫抗体的流行情况。
Transfusion. 1991 Nov-Dec;31(9):814-8. doi: 10.1046/j.1537-2995.1991.31992094668.x.
6
[Serological screening for Trypanosoma cruzi among blood donors in central Brazil].[巴西中部献血者中克氏锥虫的血清学筛查]
Bol Oficina Sanit Panam. 1992 Jul;113(1):19-27.
7
Clinical evaluation of an EIA for the sensitive and specific detection of serum antibody to Trypanosoma cruzi (Chagas' disease).一种用于灵敏且特异检测克氏锥虫血清抗体（恰加斯病）的酶免疫分析方法的临床评估。
J Infect Dis. 1992 Mar;165(3):585-8. doi: 10.1093/infdis/165.3.585.
8
A comparative study of four serological methods for diagnosis of acute and chronic Chagas' disease in Brazilian patients.四种血清学方法诊断巴西患者急性和慢性恰加斯病的比较研究。
Trop Geogr Med. 1992 Jul;44(3):210-8.
9
The epidemiology of Chagas' disease in a hyperendemic area of Cochabamba, Bolivia: a clinical study including electrocardiography, seroreactivity to Trypanosoma cruzi, xenodiagnosis, and domiciliary triatomine distribution.玻利维亚科恰班巴高流行区恰加斯病的流行病学：一项临床研究，包括心电图、对克氏锥虫的血清反应性、动物接种诊断和家庭锥蝽分布情况。
Am J Trop Med Hyg. 1992 Nov;47(5):539-46. doi: 10.4269/ajtmh.1992.47.539.
10
Comparison of the complement fixation test and counterelectrophoresis test for the detection of antibodies in Chagas disease.用于检测恰加斯病抗体的补体结合试验与对流免疫电泳试验的比较。
J Clin Microbiol. 1976 Jan;3(1):67-9. doi: 10.1128/jcm.3.1.67-69.1976.
Zotero 插件