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通过新型补体结合试验诊断美洲锥虫病（恰加斯病）。

Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test.

作者信息

Garcia E, Ramirez L E, Monteon V, Sotelo J

机构信息

National Institute of Neurology and Neurosurgery of Mexico, Mexico City.

出版信息

J Clin Microbiol. 1995 Apr;33(4):1034-5. doi: 10.1128/jcm.33.4.1034-1035.1995.

DOI:10.1128/jcm.33.4.1034-1035.1995
PMID:7790432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC228096/
Abstract

A new immunodiagnostic method of complement fixation was used for serodiagnosis of American trypanosomiasis; 92% sensitivity and 99% specificity were obtained, for an overall accuracy of 97%. This test can be used in field studies, obviating the use of most laboratory equipment and imported reagents; places where economic limitations hinder the use of other immunodiagnostic procedures; and in association with other tests for confirmation of the diagnosis.

摘要

一种新的补体结合免疫诊断方法被用于美洲锥虫病的血清学诊断；获得了92%的灵敏度和99%的特异性，总体准确率为97%。该检测可用于现场研究，无需使用大多数实验室设备和进口试剂；适用于经济条件限制妨碍使用其他免疫诊断方法的地方；还可与其他检测联合使用以确诊。

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Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test.通过新型补体结合试验诊断美洲锥虫病（恰加斯病）。
J Clin Microbiol. 1995 Apr;33(4):1034-5. doi: 10.1128/jcm.33.4.1034-1035.1995.
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引用本文的文献

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Accuracy of Diagnostic Tests for the Detection of Chagas Disease: A Systematic Review and Meta-Analysis.用于检测恰加斯病的诊断测试的准确性：一项系统评价和荟萃分析。
Diagnostics (Basel). 2022 Nov 10;12(11):2752. doi: 10.3390/diagnostics12112752.

本文引用的文献

1
American trypanosomiasis (Chagas' disease)--a tropical disease now in the United States.美洲锥虫病（恰加斯病）——一种如今在美国出现的热带疾病。
N Engl J Med. 1993 Aug 26;329(9):639-44. doi: 10.1056/NEJM199308263290909.
2
Chagas' disease diagnosis: evaluation of several tests in blood bank screening.恰加斯病诊断：血库筛查中多种检测方法的评估
Transfusion. 1993 Oct;33(10):830-4. doi: 10.1046/j.1537-2995.1993.331094054620.x.
3
Increased specificity of serodiagnosis of Chagas' disease by detection of antibody to the 72- and 90-kilodalton glycoproteins of Trypanosoma cruzi.
J Infect Dis. 1987 Mar;155(3):561-4. doi: 10.1093/infdis/155.3.561.
4
A new complement fixation test for the diagnosis of neurocysticercosis in cerebrospinal fluid.
J Neurol. 1991 Oct;238(7):379-82. doi: 10.1007/BF00319856.
5
Prevalence of antibody to Trypanosoma cruzi among blood donors in Los Angeles, California.加利福尼亚州洛杉矶市献血者中克氏锥虫抗体的流行情况。
Transfusion. 1991 Nov-Dec;31(9):814-8. doi: 10.1046/j.1537-2995.1991.31992094668.x.
6
[Serological screening for Trypanosoma cruzi among blood donors in central Brazil].[巴西中部献血者中克氏锥虫的血清学筛查]
Bol Oficina Sanit Panam. 1992 Jul;113(1):19-27.
7
Clinical evaluation of an EIA for the sensitive and specific detection of serum antibody to Trypanosoma cruzi (Chagas' disease).一种用于灵敏且特异检测克氏锥虫血清抗体（恰加斯病）的酶免疫分析方法的临床评估。
J Infect Dis. 1992 Mar;165(3):585-8. doi: 10.1093/infdis/165.3.585.
8
A comparative study of four serological methods for diagnosis of acute and chronic Chagas' disease in Brazilian patients.四种血清学方法诊断巴西患者急性和慢性恰加斯病的比较研究。
Trop Geogr Med. 1992 Jul;44(3):210-8.
9
The epidemiology of Chagas' disease in a hyperendemic area of Cochabamba, Bolivia: a clinical study including electrocardiography, seroreactivity to Trypanosoma cruzi, xenodiagnosis, and domiciliary triatomine distribution.玻利维亚科恰班巴高流行区恰加斯病的流行病学：一项临床研究，包括心电图、对克氏锥虫的血清反应性、动物接种诊断和家庭锥蝽分布情况。
Am J Trop Med Hyg. 1992 Nov;47(5):539-46. doi: 10.4269/ajtmh.1992.47.539.
10
Comparison of the complement fixation test and counterelectrophoresis test for the detection of antibodies in Chagas disease.用于检测恰加斯病抗体的补体结合试验与对流免疫电泳试验的比较。
J Clin Microbiol. 1976 Jan;3(1):67-9. doi: 10.1128/jcm.3.1.67-69.1976.