Imazato S, McCabe J F
Department of Oral Biology, Dental School, University of Newcastle upon Tyne, United Kingdom.
J Dent Res. 1994 Oct;73(10):1641-5. doi: 10.1177/00220345940730100901.
A newly developed monomer, methacryloyloxdodecylpyridinium bromide (MDPB), has an antibacterial activity against oral streptococci, and this monomer can be active even after being immobilized as one component of a cured composite. The purpose of this study was to investigate the influence of incorporation of MDPB on the curing behavior of Bis-GMA-based composites. Depth of cure, degree of cure, light-attenuating effect, and surface hardness of composites incorporating 0.4 or 0.5% MDPB were measured and compared with those of a control material without MDPB. Depth of cure of composites with MDPB, measured by means of a penetrometer, was greater than for the control (p < 0.05). Differential thermal analysis showed that composites with MDPB had a significantly greater degree of cure than the control (p < 0.05). The light-attenuating effect of MDPB composites was less than for the control (p < 0.05). No significant difference between experimental and control was obtained with respect to Vickers hardness after both one day's and seven days' storage in water. These results indicate that the incorporation of small quantities of MDPB into Bis-GMA-based composites did not adversely affect the cure performance. On the contrary, a significant, though small, improvement was observed.
一种新开发的单体，甲基丙烯酰氧基十二烷基溴化吡啶（MDPB），对口腔链球菌具有抗菌活性，并且该单体即使作为固化复合材料的一种成分固定化后仍可保持活性。本研究的目的是探讨加入MDPB对双酚A-甲基丙烯酸缩水甘油酯（Bis-GMA）基复合材料固化行为的影响。测量了含有0.4%或0.5% MDPB的复合材料的固化深度、固化程度、光衰减效应和表面硬度，并与不含MDPB的对照材料进行比较。通过针入度计测量，含MDPB的复合材料的固化深度大于对照材料（p < 0.05）。差示热分析表明，含MDPB的复合材料的固化程度明显高于对照材料（p < 0.05）。MDPB复合材料的光衰减效应小于对照材料（p < 0.05）。在水中储存一天和七天后，实验材料和对照材料的维氏硬度没有显著差异。这些结果表明，向Bis-GMA基复合材料中加入少量MDPB不会对固化性能产生不利影响。相反，观察到有显著的（尽管很小）改善。
