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研究机构中接触灰尘和大鼠尿液气传变应原。

Exposure to dust and rat urinary aeroallergens in research establishments.

作者信息

Nieuwenhuijsen M J, Gordon S, Tee R D, Venables K M, McDonald J C, Newman Taylor A J

机构信息

Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Royal Brompton and National Heart Hospital, London.

出版信息

Occup Environ Med. 1994 Sep;51(9):593-6. doi: 10.1136/oem.51.9.593.

Abstract

As part of an epidemiological study rat urinary aeroallergen (RUA) and total dust concentrations were measured at three research establishments. Personal RUA measurements in nine exposure groups over a workshift showed highest exposure for animal technicians (geometric mean (GM) = 32.4 micrograms/m3) and lowest for workers in slide production and office (GM > or = 0.1 micrograms/m3). Except for slide production workers, contact with rats, their tissues, faeces, or urine comprised less than half the work shift. Exposure during contact with rats was considerably higher. Personal RUA measurements in nine task categories showed high RUA concentrations for handling rats (GM = 68.0 micrograms/m3) and cleaning out (GM = 53.6 micrograms/m3). Traces of RUA could still be measured in tearooms inside and near offices outside the animal houses. Total dust concentrations were low.

摘要

作为一项流行病学研究的一部分,在三个研究机构测量了大鼠尿气变应原(RUA)和总粉尘浓度。在九个暴露组的一个工作日期间进行的个人RUA测量显示,动物技术员的暴露量最高(几何平均值(GM)= 32.4微克/立方米),玻片生产工人和办公室工作人员的暴露量最低(GM≥0.1微克/立方米)。除玻片生产工人外,与大鼠及其组织、粪便或尿液的接触时间不到半个工作日。与大鼠接触期间的暴露量要高得多。在九个任务类别中的个人RUA测量显示,处理大鼠(GM = 68.0微克/立方米)和清理(GM = 53.6微克/立方米)时的RUA浓度很高。在动物房内办公室和附近办公室的茶室中仍可检测到微量的RUA。总粉尘浓度较低。

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