Sorvari R, Meurman J H, Alakuijala P, Frank R M
Department of Anatomy, University of Kuopio, Finland.
Caries Res. 1994;28(4):227-32. doi: 10.1159/000261970.
The effect of fluoride varnish and solution on initial enamel erosion was studied. Enamel specimens prepared from human third molars were treated for 24 h with Duraphat varnish (2.26% F) or for 48 h with NaF solution (1.2% F), washed, and immersed in cola beverage (pH 2.6) for up to 15 min. The surface microhardness was measured using a Vickers diamond in a Leitz indentation apparatus at base-line, after fluoride treatment, and after 1, 5, and 15 min exposure to acidic drink. The specimens were then prepared and studied using a JEOL JSM-35 scanning electron microscope. The results showed that both fluoride treatment caused an increase in enamel hardness values and subsequent inhibition of softening which was statistically highly significant. Scanning electron micrographs revealed the difficulty of removing Duraphat varnish from the enamel surface, and remnants of varnish were seen irrespective of vigorous sonication in acetone. However, in areas devoid of varnish, erosion was observed as mainly irregular lesions similar to those seen in the NaF solution treated and control specimens. The present study showed that treatment of enamel with topical fluoride prior to acidic challenge can inhibit initial erosion.
研究了含氟涂料和溶液对牙釉质早期侵蚀的影响。用人的第三磨牙制备牙釉质标本，用Duraphat含氟涂料（含氟2.26%）处理24小时，或用氟化钠溶液（含氟1.2%）处理48小时，冲洗后，浸入可乐饮料（pH 2.6）中长达15分钟。在基线、氟化物处理后以及暴露于酸性饮料1分钟、5分钟和15分钟后，使用Leitz压痕仪中的维氏金刚石测量表面显微硬度。然后使用JEOL JSM - 35扫描电子显微镜制备并研究标本。结果表明，两种氟化物处理均使牙釉质硬度值增加，随后对软化的抑制在统计学上具有高度显著性。扫描电子显微镜照片显示，从牙釉质表面去除Duraphat含氟涂料存在困难，无论在丙酮中剧烈超声处理，仍可见涂料残留。然而，在没有涂料的区域，观察到的侵蚀主要是不规则病变，类似于在氟化钠溶液处理的标本和对照标本中看到的病变。本研究表明，在酸性刺激之前用局部氟化物处理牙釉质可以抑制早期侵蚀。
