Joffe R T, Bagby R M, Levitt A
Clarke Institute of Psychiatry, University of Toronto, Ont., Canada.
Am J Psychiatry. 1993 Aug;150(8):1257-8. doi: 10.1176/ajp.150.8.1257.
The authors used the anxiety summary score described by Clayton and associates to assess anxious and nonanxious subtypes of depression in a group of 134 outpatients with major depression. Patients with anxious depression were only slightly less likely to respond to their first tricyclic antidepressant than patients with nonanxious depression. When functional severity or symptom severity was controlled for, this differential treatment response did not hold.
作者采用克莱顿及其同事所描述的焦虑综合评分，对134名重度抑郁症门诊患者中的抑郁焦虑亚型和非焦虑亚型进行评估。与非焦虑性抑郁症患者相比，焦虑性抑郁症患者对其首次使用的三环类抗抑郁药产生反应的可能性仅略低。当对功能严重程度或症状严重程度进行控制时，这种差异治疗反应并不成立。
