Bentley-Phillips C B, Paulli-Jorgensen H, Marks R
Arch Dermatol Res (1975). 1977 Jan 31;257(3):233-7. doi: 10.1007/BF00741838.
The effects of prostaglandins E1 and F2alpha (PGE1 and PGF2alpha) on the growth of guinea pig epidermis have been studied in vivo. The prostaglandins were injected intradermally into guinea pigs, and tritiated thymidine was injected intraperitoneally prior to sacrifice. The autoradiographic labelling indices (L.I.) were assessed and a significant increase was found 4 h after injection of PGE1 -an effect which lasted for up to 72 h. PGF2alpha injections had no significant effect on the L.I.
已经在体内研究了前列腺素E1和F2α（PGE1和PGF2α）对豚鼠表皮生长的影响。将前列腺素皮内注射到豚鼠体内，并在处死前腹腔注射氚标记的胸腺嘧啶核苷。评估放射自显影标记指数（L.I.），发现注射PGE1后4小时有显著增加，这种效应持续长达72小时。注射PGF2α对L.I.没有显著影响。
