Lofgren R P, Wilt T J, Nichol K L, Crespin L, Pluhar R, Eckfeldt J
Department of Medicine, University of Minnesota, Minneapolis.
Am J Public Health. 1993 Feb;83(2):267-9. doi: 10.2105/ajph.83.2.267.
We conducted a double-blind, placebo-controlled crossover study to determine the effects of fish oil supplementation on blood pressure in middle-aged men. Subjects were randomly assigned to consume either 20 g of fish oil or safflower oil for 12 weeks and then consume the other oil for an additional 12 weeks after a 4-week washout period. We found no significant changes from the pretreatment value in systolic or diastolic blood pressure with the use of fish oil supplements. In addition, there were no significant differences in the posttreatment blood pressures comparing the fish and safflower oil phases of the study.
我们进行了一项双盲、安慰剂对照的交叉研究，以确定补充鱼油对中年男性血压的影响。受试者被随机分配，连续12周服用20克鱼油或红花油，然后在4周的洗脱期后，再连续12周服用另一种油。我们发现，使用鱼油补充剂后，收缩压或舒张压与治疗前的值相比没有显著变化。此外，在研究的鱼油和红花油阶段，治疗后的血压没有显著差异。
