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用减毒的小反刍兽疫病毒疫苗接种山羊预防牛瘟。

Protection of goats against rinderpest by vaccination with attenuated peste des petits ruminants virus.

作者信息

Couacy-Hymann E, Bidjeh K, Angba A, Domenech J, Diallo A

机构信息

CIRAD-EMVT, France.

出版信息

Res Vet Sci. 1995 Sep;59(2):106-9. doi: 10.1016/0034-5288(95)90041-1.

DOI:10.1016/0034-5288(95)90041-1
PMID:8525096
Abstract

The ability of the attenuated peste des petits ruminants vaccine virus to protect small ruminants against virulent rinderpest virus was investigated. Out of four susceptible goats that were infected with the highly virulent Saudi strain of rinderpest virus by intranasal ioculation, three developed mild clinical signs of disease and infected susceptible in-contact goats and cattle with rinderpest virus. However, four goats which had been vaccinated with the attenuated peste des petits ruminants virus resisted challenge with virulent rinderpest virus and did not infect susceptible in-contact animals.

摘要

对减毒的小反刍兽疫疫苗病毒保护小反刍动物抵御强毒牛瘟病毒的能力进行了研究。通过鼻内接种,用高毒力的沙特牛瘟病毒株感染了4只易感山羊,其中3只出现了轻微的疾病临床症状,并将牛瘟病毒传染给了易感的接触山羊和牛。然而,4只接种了减毒小反刍兽疫病毒的山羊抵抗了强毒牛瘟病毒的攻击,并未感染易感的接触动物。

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