Walters A S
Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903-0019, USA.
Mov Disord. 1995 Sep;10(5):634-42. doi: 10.1002/mds.870100517.
A large International Restless Legs Syndrome (RLS) Study Group has been formed. As its first task, the group has taken upon itself the role of defining the clinical features of the RLS. As minimal criteria for diagnosis, the group proposes the following four features: (a) desire to move the extremities, often associated with paresthesias/dysesthesias; (b) motor restlessness; (c) worsening of symptoms at rest with at least temporary relief by activity, and (d) worsening of symptoms in the evening or night. Other features commonly seen in RLS include sleep disturbance, periodic limb movements in sleep and similar involuntary movements while awake, a normal neurological examination in the idiopathic form, a tendency for the symptoms to be worse in middle to older age, and, in some cases, a family history suggestive of an autosomal dominant mode of inheritance.
一个大型国际不宁腿综合征（RLS）研究小组已经成立。作为其首要任务，该小组承担起了定义RLS临床特征的职责。作为诊断的最低标准，该小组提出了以下四个特征：（a）肢体移动的欲望，常伴有感觉异常/感觉障碍；（b）运动性不安；（c）休息时症状加重，活动后至少暂时缓解，以及（d）傍晚或夜间症状加重。RLS中常见的其他特征包括睡眠障碍、睡眠中的周期性肢体运动以及清醒时类似的不自主运动、特发性形式的神经系统检查正常、症状在中年至老年时往往更严重，以及在某些情况下提示常染色体显性遗传模式的家族史。
