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抗病毒硫酸化α-D-(1→3)-连接甘露聚糖的结构分析

Structural analysis of antiviral sulfated alpha-D-(1-->3)-linked mannans.

作者信息

Kolender A A, Matulewicz M C, Cerezo A S

机构信息

Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.

出版信息

Carbohydr Res. 1995 Aug 25;273(2):179-85. doi: 10.1016/0008-6215(95)00078-8.

DOI:10.1016/0008-6215(95)00078-8
PMID:8565005
Abstract

The structures of two alpha-(1-->3)-alpha-D-xylo-mannans were determined. The different antiviral activity of the xylo-mannans from Nothogenia fastigiata was explained on the basis of a flexible backbone, molecular size, content and distribution of sulfate groups and of the single stubs of beta-(1-->2)-linked D-xylose.

摘要

确定了两种α-(1→3)-α-D-木糖甘露聚糖的结构。基于柔性主链、分子大小、硫酸基团的含量和分布以及β-(1→2)-连接的D-木糖单支链,解释了来自尖叶南洋杉的木糖甘露聚糖具有不同抗病毒活性的原因。

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