Cheah K S, Osborne D J
Biochem J. 1977 Apr 1;163(1):141-4. doi: 10.1042/bj1630141.
Comparisons of nuclease digestions of chromatin in nuclei from rye embryos and rat liver show that their nucleosomal DNA is similar, i.e. DNA subunits consist of 200 base-pair repeats with 140 base-pair cores of identical substructure. The identical nucleosome structure is present in nuclei from cells of rye embryos that have been non-viable (i.e. dead) for more than 7 years. These findings indicate a high degree of stability of the DNA-histone complex and are consistent with conservation of the nucleosomal structure of chromatin during evolution.
对黑麦胚胎细胞核和大鼠肝脏细胞核中的染色质进行核酸酶消化比较，结果表明它们的核小体DNA相似，即DNA亚基由200个碱基对的重复序列组成，其140个碱基对的核心具有相同的亚结构。在已死亡超过7年的黑麦胚胎细胞的细胞核中也存在相同的核小体结构。这些发现表明DNA-组蛋白复合物具有高度稳定性，并且与染色质核小体结构在进化过程中的保守性相一致。
