Yaghoobi-Ershadi M R, Javadian E
Department of Medical Entomology, School of Public Health, Teheran University of Medical Sciences, Iran.
Med Vet Entomol. 1996 Apr;10(2):181-4. doi: 10.1111/j.1365-2915.1996.tb00726.x.
In preparation for field trials of killed Leishmania major vaccine, natural infections with Leishmania promastigotes were monitored in Phlebotomine sandfly vectors from villages of Borkhar rural district, northeast of Isfahan in central Iran, where L.major zymodeme MON-26 ( = LON-1) has been identified as causing zoonotic cutaneous leishmaniasis (ZCL). Sandflies were collected and dissected weekly, from burrows of rodent colonies, during the "sandfly season', June-October 1991. Leptomonad infection rates were 12% of 26 Phlebotomus ansarii, 8% of 280 P.caucasicus, 11% of 1042 P.papatasi and none of 126 Sergentomyia sintoni, being greatest during late August through September, coinciding with peak activity of the sandflies, 2-3 months before the highest incidence of ZCL human cases in November-December.
在准备硕大利什曼原虫灭活疫苗的现场试验时，对来自伊朗中部伊斯法罕东北部博尔哈尔农村地区村庄的白蛉媒介中利什曼原鞭毛虫的自然感染情况进行了监测，在该地区已确定硕大利什曼原虫酶谱型MON - 26（= LON - 1）可引起动物源性皮肤利什曼病（ZCL）。在1991年6月至10月的“白蛉季节”，每周从啮齿动物聚居地的洞穴中收集并解剖白蛉。在26只安氏白蛉中，利什曼原虫感染率为12%；在280只高加索白蛉中，感染率为8%；在1042只巴氏白蛉中，感染率为11%；而在126只辛氏司蛉中未发现感染。感染率在8月下旬至9月期间最高，与白蛉的活动高峰期一致，比11月至12月ZCL人类病例的最高发病率提前2 - 3个月。
