γ-氨基丁酸B型（GABAB）受体拮抗剂CGP 36742和促智药奥拉西坦有助于长期记忆的形成。
The GABAB receptor antagonist CGP 36,742 and the nootropic oxiracetam facilitate the formation of long-term memory.
作者信息
Mondadori C, Möbius H J, Borkowski J
机构信息
Pharmaceutical Research Department, CIBA Ltd., Basel, Switzerland.
出版信息
Behav Brain Res. 1996 May;77(1-2):223-5. doi: 10.1016/0166-4328(95)00222-7.
PMID:8762175
Abstract
The memory-enhancing effects of a single treatment with the GABAB antagonist CGP 36,742 (10 mg/kg) or the nootropic agent oxiracetam (100 mg/kg) given immediately after a learning experience ('post-trial') remain detectable for at least 4 months thereafter. This indicates that in all probability these substances facilitate the formation of the long-term memory trace.
摘要
在学习经历后即刻（“试验后”）单次给予GABAB拮抗剂CGP 36,742（10毫克/千克）或益智药奥拉西坦（100毫克/千克）的记忆增强作用，在此后至少4个月内仍可检测到。这表明很可能这些物质促进了长期记忆痕迹的形成。
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