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饮食和体育锻炼干预计划对瑞典吸烟和不吸烟男性冠心病风险的影响。

Effect of diet and physical exercise intervention programmes on coronary heart disease risk in smoking and non-smoking men in Sweden.

作者信息

Näslund G K, Fredrikson M, Hellénius M L, de Faire U

机构信息

Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden.

出版信息

J Epidemiol Community Health. 1996 Apr;50(2):131-6. doi: 10.1136/jech.50.2.131.

Abstract

STUDY OBJECTIVE

To investigate differences between smokers and non-smokers in health behaviour, cardiovascular risk factors, coronary heart disease (CHD) risks, health knowledge, health attitudes, and compliance with a CHD prevention programme.

DESIGN

Differences between smokers and non-smokers were studied via medical examinations, questionnaires, physical exercise activity logs, and food record sheets. Data were analysed using univariate and multivariate analyses. The five and 10 year CHD risks were assessed using the Framingham CHD risk estimate.

SETTING

The Karolinska Hospital, Stockholm, and Sollentuna Primary Health Centre, Sollentuna, Sweden.

PARTICIPANTS

The analyses were based on 158 healthy smoking and non-smoking men aged 35-60 years with raised cardiovascular risk factors who enrolled in controlled, randomised six month diet and exercise programmes.

MAIN RESULTS

Discriminant analysis suggested that smokers, compared with non-smokers, were characterised by a higher alcohol energy percent, lower HDL cholesterol concentration, lower systolic blood pressure, and a higher plasminogen activator inhibitor-1 (PAI-1) value. Knowledge of the risk factors for CHD was not a discriminating factor. Both smokers and non-smokers increased the exercise taken, improved their diet, and lowered their CHD risk. Before, as well as after the intervention, smokers had a higher CHD risk than non-smokers.

CONCLUSIONS

The best CHD prevention action that could be taken by smokers would of course be to quit smoking. Those who cannot stop should be encouraged to improve their diet and increase the amount of physical exercise they take in order to reduce the health hazards of their smoking behaviour.

摘要

研究目的

调查吸烟者与非吸烟者在健康行为、心血管危险因素、冠心病(CHD)风险、健康知识、健康态度以及对冠心病预防计划的依从性方面的差异。

设计

通过医学检查、问卷调查、体育活动日志和食物记录单研究吸烟者与非吸烟者之间的差异。使用单变量和多变量分析对数据进行分析。采用弗雷明汉姆冠心病风险评估法评估5年和10年冠心病风险。

地点

瑞典斯德哥尔摩的卡罗林斯卡医院和索伦特纳的索伦特纳初级卫生保健中心。

参与者

分析基于158名年龄在35 - 60岁、心血管危险因素升高的健康吸烟和非吸烟男性,他们参加了为期6个月的对照随机饮食和运动计划。

主要结果

判别分析表明,与非吸烟者相比,吸烟者的特征是酒精能量百分比更高、高密度脂蛋白胆固醇浓度更低、收缩压更低以及纤溶酶原激活物抑制剂-1(PAI - 1)值更高。对冠心病危险因素的了解不是一个区分因素。吸烟者和非吸烟者都增加了运动量、改善了饮食并降低了冠心病风险。在干预之前和之后,吸烟者的冠心病风险都高于非吸烟者。

结论

吸烟者能够采取的最佳冠心病预防行动当然是戒烟。对于那些无法戒烟的人,应鼓励他们改善饮食并增加运动量,以减少吸烟行为对健康的危害。

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