Gupta L Y, Marmor M F
Department of Ophthalmology, Stanford University Medical Center, USA.
Doc Ophthalmol. 1995;91(2):101-7. doi: 10.1007/BF01203689.
The pathophysiology of central serous chorioretinopathy is incompletely understood but appears to involve the retinal pigment epithelium. We recorded consecutively the fast oscillation, hyperosmolarity response, acetazolamide response, and light peak from four patients with active central serous chorioretinopathy and three normal subjects to determine whether the affected eyes showed any electrophysical abnormalities. We found essentially no differences in any of the four responses between the active and the inactive eyes of the patients or between patients and normal subjects. Whatever retinal pigment epithelial dysfunction exists in central serous chorioretinopathy is unassociated with clinically evident changes in these retinal pigment epithelial electrophysiologic responses.
中心性浆液性脉络膜视网膜病变的病理生理学尚未完全明确，但似乎涉及视网膜色素上皮。我们连续记录了4例活动性中心性浆液性脉络膜视网膜病变患者和3名正常受试者的快速振荡、高渗反应、乙酰唑胺反应及光峰，以确定患眼是否存在任何电生理异常。我们发现，患者患眼与未患眼之间以及患者与正常受试者之间，这四种反应中的任何一种均无本质差异。中心性浆液性脉络膜视网膜病变中存在的任何视网膜色素上皮功能障碍，均与这些视网膜色素上皮电生理反应的临床明显变化无关。
