使用宫颈刷和艾尔斯伯里刮片进行宫颈细胞学采样的充分性：一项基于人群的随机对照试验。
Adequacy of cervical cytology sampling with the Cervex brush and the Aylesbury spatula: a population based randomised controlled trial.
作者信息
Dey P, Collins S, Desai M, Woodman C
机构信息
Centre for Cancer Epidemiology, University of Manchester.
出版信息
BMJ. 1996 Sep 21;313(7059):721-3. doi: 10.1136/bmj.313.7059.721.
OBJECTIVE
To compare the adequacy of cervical cytology sampling with two sampling instruments commonly used in primary care-namely, the Aylesbury spatula and the Cervex brush.
DESIGN
Pair matched, population based randomised controlled trial.
SETTING
86 general practices and family planning clinics in Greater Manchester.
SUBJECTS
15 882 cervical smears taken from women aged 20-64 years as part of the national cervical screening programme.
INTERVENTIONS
Participating centres were allocated to sample with either the Cervex brush or the Aylesbury spatula.
MAIN OUTCOME MEASURE
Inadequate smear rate.
RESULTS
5.4% and 5.5% (433/8086 and 426/7796) of smears taken with the Cervex brush and the Aylesbury spatula respectively were reported as inadequate (odds ratio 0.95; 95% confidence interval 0.74 to 1.22).
CONCLUSION
The Cervex brush offers no advantage over the Aylesbury spatula in reducing inadequate smear rates in the primary care setting.
目的
比较在初级保健中常用的两种取样工具——即艾尔斯伯里刮板和宫颈刷——进行宫颈细胞学取样的充分性。
设计
配对匹配、基于人群的随机对照试验。
地点
大曼彻斯特的86家全科诊所和计划生育诊所。
研究对象
作为国家宫颈筛查计划的一部分，从20 - 64岁女性中采集的15882份宫颈涂片。
干预措施
将参与的中心分配为使用宫颈刷或艾尔斯伯里刮板进行取样。
主要观察指标
涂片不合格率。
结果
分别用宫颈刷和艾尔斯伯里刮板采集的涂片中有5.4%和5.5%（433/8086和426/7796）报告为不合格（优势比0.95；95%置信区间0.74至1.22）。
结论
在初级保健环境中，宫颈刷在降低涂片不合格率方面并不比艾尔斯伯里刮板更具优势。
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