Jacquet L, Hanique G, Glorieux D, Matte P, Goenen M
Saint-Luc University Hospital, Cardio-thoracic Intensive Care Unit, Brussels, Belgium.
Intensive Care Med. 1996 Oct;22(10):1125-9. doi: 10.1007/BF01699240.
To evaluate the accuracy of cardiac output measurement obtained by a new continuous thermodilution cardiac output (CCO) pulmonary artery catheter compared to intermittent thermodilution (TCO) and the direct Fick method.
Prospective open trial.
University hospital, intensive care unit.
23 patients (15 surgical, 8 non-surgical) were monitored with the Intellicath pulmonary catheter. Cardiac output was evaluated by the three methods every 4 to 6h as long as the pulmonary artery catheter was necessary (8-96 h).
The correlation coefficient between CCO and TCO was 0.92, no systematic bias was observed, and the relative error increased from 13.9% for a cardiac output of 21/min to 23.7% for an output of 101/min. When comparing CCO and Fick, the correlation coefficient was 0.89, no bias was detected, and the relative error increased from 20.4% for outputs of 21/min to 27.2% for outputs of 101/min.
CCO provides clinically acceptable measurements. At high cardiac outputs, the difference with other methods increases and the results must be cautiously interpreted.
评估一种新型连续热稀释心输出量（CCO）肺动脉导管所测得的心输出量与间歇性热稀释法（TCO）及直接Fick法相比的准确性。
前瞻性开放试验。
大学医院重症监护病房。
使用Intellicath肺动脉导管对23例患者（15例外科手术患者，8例非外科手术患者）进行监测。只要需要留置肺动脉导管（8 - 96小时），每4至6小时用三种方法评估心输出量。
CCO与TCO之间的相关系数为0.92，未观察到系统偏差，相对误差从心输出量为21/min时的13.9%增加至心输出量为101/min时的23.7%。比较CCO与Fick法时，相关系数为0.89，未检测到偏差，相对误差从心输出量为21/min时的20.4%增加至心输出量为101/min时的27.2%。
CCO可提供临床可接受的测量结果。在心输出量较高时，与其他方法的差异增大，对结果的解读必须谨慎。
