Watanabe J, Kawabata J, Kurihara H, Niki R
Department of Bioscience and Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Biosci Biotechnol Biochem. 1997 Jan;61(1):177-8. doi: 10.1271/bbb.61.177.
alpha-Glucosidase inhibitory activity was found in aqueous methanol extracts of tochu-cha, dried leaves of Eucommia ulmoides (Eucommiaceae). Five active principles against yeast enzyme were isolated and characterized. Among them, quercetin (1, Ki: 8.5 x 10(-6) M) was considered to contribute mostly to the activity of the tochu leaves. In regard to an animal alpha-glucosidase, rat intestinal sucrase activity was also inhibited by 1.
在杜仲科杜仲干燥叶杜仲茶的甲醇水提取物中发现了α-葡萄糖苷酶抑制活性。分离并鉴定了五种针对酵母酶的活性成分。其中，槲皮素（1，Ki：8.5×10⁻⁶ M）被认为对杜仲叶的活性贡献最大。对于动物α-葡萄糖苷酶，大鼠肠道蔗糖酶活性也被1抑制。
