通过空气张力测量法对胃内PCO2测量进行体外评估。
In vitro evaluation of intragastric PCO2 measurement by air tonometry.
作者信息
Kolkman J J, Zwaarekant L J, Boshuizen K, Groeneveld A B, Meuwissen S G
机构信息
Department of Gastroenterology, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
出版信息
J Clin Monit. 1997 Mar;13(2):115-9. doi: 10.1023/a:1007335622132.
OBJECTIVE
To assess the in vitro performance of a new device, the Tonocap, for semi-continuous air tonometry of regional PCO2 in the gastrointestinal tract.
METHODS
The tonometer consists of an air filled balloon-tipped catheter, connected to a prototype Tonocap system. The tonometer was placed in saline baths at steady-state PCO2's ranging from 0 to 105 torr, to evaluate bias, precision and reproducibility to PCO2 measurements. The response time was defined as the time needed to detect 95% of an instantaneous change in bath PCO2.
RESULTS
The bias of the PCO2 measurement (mean +/- SD) was -2 +/- 2% and reproducibility (coefficient of variation) was 2 +/- 1%. The response time was 19 +/- 2 min.
CONCLUSIONS
Tonocap air tonometry is simple and eliminates most sources of error associated with conventional saline tonometry. The bias, precision, reproducibility and response time in vitro are consistent with a clinically reliable device.
目的
评估一种新型设备——眼压计（Tonocap）用于胃肠道局部二氧化碳分压（PCO2）半连续气测眼压法的体外性能。
方法
眼压计由一个充气球囊尖端导管组成，连接到一个原型眼压计系统。将眼压计置于稳态PCO2范围为0至105托的盐浴中，以评估PCO2测量的偏差、精密度和可重复性。响应时间定义为检测盐浴PCO2瞬间变化的95%所需的时间。
结果
PCO2测量的偏差（平均值±标准差）为-2±2%，可重复性（变异系数）为2±1%。响应时间为19±2分钟。
结论
眼压计气测眼压法简单，消除了与传统盐溶液眼压测量相关的大多数误差来源。体外的偏差、精密度、可重复性和响应时间与临床可靠设备一致。
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