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干扰素处理的人淋巴细胞上HLA抗原和β2-微球蛋白的表达增强。

Enhanced expression of HLA antigens and beta 2-microglobulin on interferon-treated human lymphoid cells.

作者信息

Fellous M, Kamoun M, Gresser I, Bono R

出版信息

Eur J Immunol. 1979 Jun;9(6):446-9. doi: 10.1002/eji.1830090606.

DOI:10.1002/eji.1830090606
PMID:91516
Abstract

Human leukocyte interferon increased the expression of HLA-A, B antigens and beta 2-microglobulin on two lines of human lymphoblastoid cells and on peripheral blood lymphocytes. No effect was observed on the expression of HLA-DR antigens.

摘要

人白细胞干扰素可增加两株人淋巴母细胞系及外周血淋巴细胞上HLA - A、B抗原和β2 -微球蛋白的表达。未观察到对HLA - DR抗原表达的影响。

相似文献

1
Enhanced expression of HLA antigens and beta 2-microglobulin on interferon-treated human lymphoid cells.干扰素处理的人淋巴细胞上HLA抗原和β2-微球蛋白的表达增强。
Eur J Immunol. 1979 Jun;9(6):446-9. doi: 10.1002/eji.1830090606.
2
Enhanced expression in vivo of HLA-ABC antigens and beta 2-microglobulin on human lymphoid cells induced by human interferon-alpha in patients with lung cancer. Enhanced expression of class I major histocompatibility antigens prior to treatment.α-干扰素诱导肺癌患者体内人淋巴细胞上HLA-ABC抗原及β2-微球蛋白的表达增强。治疗前I类主要组织相容性抗原表达增强。
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Alpha-interferon induces enhanced expression of HLA-ABC antigens and beta-2-microglobulin in vivo and in vitro in various subsets of human lymphoid cells.α-干扰素在体内和体外均可诱导人淋巴细胞各亚群中HLA-ABC抗原和β2-微球蛋白的表达增强。
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Enhanced expression of melanoma-associated antigens and beta 2-microglobulin on cultured human melanoma cells by interferon.干扰素对培养的人黑色素瘤细胞上黑色素瘤相关抗原和β2-微球蛋白表达的增强作用
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[Effect of interferon on human cell lines which do not express class I transplantation antigens: K 562 and Daudi. Presence of a pseudo-messenger RNA of beta 2-microglobulin in Daudi cell line].[干扰素对不表达I类移植抗原的人细胞系（K 562和Daudi）的作用：Daudi细胞系中β2-微球蛋白假信使RNA的存在]
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Recombinant interferon-gamma can induce the expression of HLA-DR and -DC on DR-negative melanoma cells and enhance the expression of HLA-ABC and tumor-associated antigens.重组干扰素-γ可诱导DR阴性黑色素瘤细胞上HLA-DR和-DC的表达，并增强HLA-ABC和肿瘤相关抗原的表达。
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Role of antigen density in immune lysis of interferon-treated human lymphoid cells: analysis with monoclonal antibodies to the HLA-A,B antigenic molecular complex and to Ia-like antigens.抗原密度在干扰素处理的人淋巴细胞免疫裂解中的作用：用针对HLA - A、B抗原分子复合物和Ia样抗原的单克隆抗体进行分析。
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Corticosteroids decrease the expression of beta 2-microglobulin and histocompatibility antigens on human peripheral blood lymphocytes in vitro.在体外，皮质类固醇可降低人外周血淋巴细胞上β2-微球蛋白和组织相容性抗原的表达。
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Enhanced expression of beta2-microglobulin and HLA antigens on human lymphoid cells by interferon.干扰素对人淋巴细胞上β2-微球蛋白和HLA抗原的增强表达
Proc Natl Acad Sci U S A. 1978 Dec;75(12):6215-9. doi: 10.1073/pnas.75.12.6215.
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Enhancement by interferon of membrane HLA antigens in patients with combined immunodeficiency with defective HLA expression.干扰素对伴有HLA表达缺陷的联合免疫缺陷患者膜HLA抗原的增强作用。
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引用本文的文献

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Interferons in cancer immunoediting: sculpting metastasis and immunotherapy response.干扰素在癌症免疫编辑中的作用：塑造转移和免疫治疗反应。
J Clin Invest. 2021 Jan 4;131(1). doi: 10.1172/JCI143296.
2
Inhibition of growth, transformation, and expression of human papillomavirus type 16 E7 in human keratinocytes by alpha interferons.α干扰素对人角质形成细胞中16型人乳头瘤病毒E7生长、转化及表达的抑制作用
J Virol. 1993 Jun;67(6):3396-403. doi: 10.1128/JVI.67.6.3396-3403.1993.
3
Control of HLA-A,B,C synthesis and expression in interferon-treated cells.
干扰素处理细胞中HLA - A、B、C合成与表达的调控
EMBO J. 1982;1(3):345-9. doi: 10.1002/j.1460-2075.1982.tb01172.x.
4
Differential effects of gamma interferon on expression of HLA class II molecules controlled by the DR and DC loci.γ干扰素对由DR和DC基因座控制的HLA II类分子表达的不同影响。
Infect Immun. 1983 Oct;42(1):122-5. doi: 10.1128/iai.42.1.122-125.1983.
5
Molecular cloning and sequence of partial cDNA for interferon-induced (2'-5')oligo(A) synthetase mRNA from human cells.人细胞中干扰素诱导的（2'-5'）寡腺苷酸合成酶mRNA部分cDNA的分子克隆与序列分析
Proc Natl Acad Sci U S A. 1983 Aug;80(16):4904-8. doi: 10.1073/pnas.80.16.4904.
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Increased expression of human monocyte HLA-DR antigens and Fc gamma receptors in response to human interferon in vivo.体内人干扰素刺激后人类单核细胞HLA - DR抗原及Fcγ受体表达增加。
Clin Exp Immunol. 1983 Sep;53(3):739-43.
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Induction of Ia antigen in rat epidermal cells and gut epithelium by immunological stimuli.免疫刺激诱导大鼠表皮细胞和肠上皮细胞Ia抗原的产生。
J Exp Med. 1982 Dec 1;156(6):1665-76. doi: 10.1084/jem.156.6.1665.
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The interferons.干扰素
Clin Exp Immunol. 1983 Oct;54(1):1-13.
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Enhancement by interferon of membrane HLA antigens in patients with combined immunodeficiency with defective HLA expression.干扰素对伴有HLA表达缺陷的联合免疫缺陷患者膜HLA抗原的增强作用。
Clin Exp Immunol. 1983 Apr;52(1):173-8.
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Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA.人细胞中干扰素诱导的56,000道尔顿蛋白及其mRNA：cDNA的分子克隆与部分序列
Nucleic Acids Res. 1983 Mar 11;11(5):1213-26. doi: 10.1093/nar/11.5.1213.