Hellemans S, Dens J, Knockaert D
Department of Cardiology, Gasthuisberg University Hospital, Catholic University Leuven, Belgium.
Heart. 1997 Jun;77(6):576-8. doi: 10.1136/hrt.77.6.576.
The Churg-Strauss syndrome (CSS) is a rare systemic disease characterised by vasculitis and peripheral eosinophilia in patients with an atopic constitution. Cardiac involvement is an important cause of morbidity and mortality yet coronary involvement is very rarely documented. We report the case of a 38 year old man presenting with fulminant heart failure. Coronary arteriography demonstrated extensive focal vasculopathy consistent with vasculitis. The diagnosis of CSS was established based upon the classical diagnostic criteria and corticosteroid treatment resulted in a spectacular remission of disease activity.
变应性肉芽肿性血管炎(CSS)是一种罕见的全身性疾病,其特征为患有特应性体质的患者出现血管炎和外周嗜酸性粒细胞增多。心脏受累是发病和死亡的重要原因,但冠状动脉受累的记录却非常罕见。我们报告了一例38岁男性患者,其表现为暴发性心力衰竭。冠状动脉造影显示广泛的局灶性血管病变,符合血管炎表现。根据经典诊断标准确诊为CSS,皮质类固醇治疗使疾病活动显著缓解。