Moses R, Rodda M, Griffiths R
Illawarra Area Health Service, New South Wales.
Aust N Z J Obstet Gynaecol. 1997 Aug;37(3):279-81. doi: 10.1111/j.1479-828x.1997.tb02408.x.
In Europid populations, patients with non-insulin-dependent diabetes mellitus (NIDDM) are more than twice as likely to have a mother than a father with diabetes. We have examined this aspect in an Australian population. For this purpose records of 1,000 consecutive patients with NIDDM were reviewed. A history of diabetes was present in 193 mothers (19.3%) and in only 86 fathers (8.6%) (p < 0.0001). The predominance of maternal history of diabetes in patients with NIDDM is suggestive of a maternal transmission of this disorder. This metabolic tendency may develop due to an adverse intrauterine environment in women with undiagnosed gestational diabetes mellitus.
在欧洲人群中，非胰岛素依赖型糖尿病（NIDDM）患者的母亲患有糖尿病的可能性是父亲的两倍多。我们在澳大利亚人群中研究了这一情况。为此，回顾了1000例连续的NIDDM患者的记录。193名母亲（19.3%）有糖尿病史，而只有86名父亲（8.6%）有糖尿病史（p<0.0001）。NIDDM患者中母亲有糖尿病史占主导，提示这种疾病存在母系遗传。这种代谢倾向可能是由于未被诊断出的妊娠期糖尿病女性子宫内不良环境所致。
