Donaldson A I
Institute for Animal Health, Pirbright Laboratory, Woking, Surrey, United Kingdom.
Rev Sci Tech. 1997 Apr;16(1):117-24. doi: 10.20506/rst.16.1.1013.
A review of epidemics of foot and mouth disease (FMD) has highlighted the important role which raw (untreated) milk can play in the spread of the disease in a country which is normally free of FMD and whose cattle are not routinely vaccinated. The greatest hazard is likely to be in the early stages of an outbreak, before disease control measures have been implemented. The spread of FMD through milk can be prevented by the effective application of control measures combined with 'codes of practice' for the treatment of potentially infected milk. The author considers the probable mechanisms of transmission of FMD by milk and dairy products. These mechanisms are based on the quantities of virus excreted in milk, the survival of the virus under various management and manufacturing conditions and the minimum doses required to initiate infection in susceptible animals by different routes. The key points for consideration when making a risk assessment of the importation of milk and dairy products are also discussed.
一项对口蹄疫疫情的综述强调了生(未处理)牛奶在一个通常无口蹄疫且牛群未常规接种疫苗的国家中,在疾病传播方面可能发挥的重要作用。最大的风险可能出现在疫情爆发的早期阶段,即在疾病控制措施实施之前。通过有效实施控制措施并结合处理潜在感染牛奶的“操作规范”,可以防止口蹄疫通过牛奶传播。作者考虑了口蹄疫通过牛奶和乳制品传播的可能机制。这些机制基于牛奶中排出的病毒量、病毒在各种管理和生产条件下的存活情况以及通过不同途径引发易感动物感染所需的最小剂量。文中还讨论了在对牛奶和乳制品进口进行风险评估时需要考虑的关键点。