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哈萨克斯坦母乳中氯化污染物暴露情况分析:哈萨克斯坦南部的多氯联苯和有机氯农药

Analysis of breast milk to assess exposure to chlorinated contaminants in Kazakstan: PCBs and organochlorine pesticides in southern Kazakstan.

作者信息

Hooper K, Hopper K, Petreas M X, She J, Visita P, Winkler J, McKinney M, Mok M, Sy F, Garcha J, Gill M, Stephens R D, Semenova G, Sharmanov T, Chuvakova T, Hopper K

机构信息

Hazardous Materials Laboratory, California EPA, Berkeley, CA 94704-1011, USA.

出版信息

Environ Health Perspect. 1997 Nov;105(11):1250-4. doi: 10.1289/ehp.971051250.

Abstract

Organochlorine pesticides (OC) and polychlorinated biphenyls (PCBs) were measured in samples of breast milk taken from 92 donors representative of regional populations in southern Kazakstan. The World Health Organization protocol for assessing levels of chlorinated contaminants in breast milk was followed. The most prevalent OC residues were beta-hexachlorocyclohexane (beta-HCH), p,p'-DDE, p,p'-DDT, hexachlorobenzene, and alpha-HCH. The measured levels of beta-HCH were among the highest reported in the published literature. Data from Aralsk, near the Aral Sea, indicated continuing DDT exposure. Overall PCB-toxic equivalent levels (22 pg/g fat) were similar to those reported in industrialized European countries. PCBs were highest in Atyrau in the Caspian oilfields.

摘要

对来自哈萨克斯坦南部地区具有代表性的92位母乳捐赠者的样本进行了有机氯农药(OC)和多氯联苯(PCB)的检测。检测遵循了世界卫生组织评估母乳中氯化污染物水平的方案。最普遍的有机氯残留为β-六氯环己烷(β-HCH)、p,p'-滴滴伊(p,p'-DDE)、p,p'-滴滴涕(p,p'-DDT)、六氯苯和α-六氯环己烷(α-HCH)。所测β-六氯环己烷水平在已发表文献报道中处于最高之列。来自咸海附近阿拉尔斯克的数据表明滴滴涕仍在持续造成接触。多氯联苯的总毒性当量水平(22皮克/克脂肪)与欧洲工业化国家报道的水平相似。多氯联苯在里海油田的阿特劳含量最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f307/1470329/5c46a3e6c4c5/envhper00324-0099-a.jpg

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