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挪威孕妇中弓形虫特异性免疫球蛋白G抗体的患病率。

Prevalence of Toxoplasma gondii specific immunoglobulin G antibodies among pregnant women in Norway.

作者信息

Jenum P A, Kapperud G, Stray-Pedersen B, Melby K K, Eskild A, Eng J

机构信息

Department of Bacteriology, National Institute of Public Health, Oslo, Norway.

出版信息

Epidemiol Infect. 1998 Feb;120(1):87-92. doi: 10.1017/s0950268897008480.

Abstract

During one year from June 1992 serum IgG antibodies to Toxoplasma gondii among 35,940 pregnant women were measured in a cross-sectional study conducted in Norway. The overall prevalence was 10.9%. The lowest prevalences were detected in the north (6.7%) and in the inland counties (8.2%). A significantly higher prevalence was detected in the southern counties (13.4%) where a mild, coastal climate prevails. Women with foreign names had a higher prevalence (22.6%) than women with Norwegian names (10.0%). The high prevalence among women living in the capital city (Oslo) as compared to other cities and rural areas (13.2% vs. 10.1% and 10.2% respectively), was explained by the higher proportion of foreign women in Oslo. Prevalence significantly increased with age in women over 34 years old. This increase was only detected among women with Norwegian names. An increase in prevalence according to number of children was detected. Women without children had a prevalence of 8.8% while women with three children or more had a prevalence of 14.9%. Multivariate analyses showed that being seropositive was independently associated with county of residence, age, nationality and number of children.

摘要

1992年6月起的一年时间里,在挪威开展的一项横断面研究中,对35940名孕妇的血清抗弓形虫IgG抗体进行了检测。总体患病率为10.9%。患病率最低的是北部地区(6.7%)和内陆郡县(8.2%)。在气候温和的沿海地区的南部郡县,患病率显著更高(13.4%)。有外国名字的女性患病率(22.6%)高于有挪威名字的女性(10.0%)。与其他城市和农村地区相比,首都奥斯陆女性的患病率较高(分别为13.2%、10.1%和10.2%),这是因为奥斯陆外国女性的比例更高。34岁以上女性的患病率随年龄显著增加。这种增加仅在有挪威名字的女性中被发现。根据子女数量,患病率也有所增加。未育女性的患病率为8.8%,而育有三个或更多子女的女性患病率为14.9%。多变量分析表明,血清反应阳性与居住郡县、年龄、国籍和子女数量独立相关。

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