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新发人畜共患病:兽医行业面临的挑战与机遇

New emerging zoonoses: a challenge and an opportunity for the veterinary profession.

作者信息

Chomel B B

机构信息

Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis 95616, USA.

出版信息

Comp Immunol Microbiol Infect Dis. 1998 Jan;21(1):1-14. doi: 10.1016/s0147-9571(97)00018-0.

Abstract

The concept of emerging infectious diseases appeared in the late 1980s, when major outbreaks occurred around the globe and surprised many scientists who considered infectious diseases to be maladies of the past or limited to the under-developed world. Several reports identified erosion of the public health infrastructure among the factors contributing to new and re-emerging infectious diseases. As indicated by Morse, "Disease emergence often follows ecological changes caused by human activities such as agriculture or agricultural change, migration, urbanization, deforestation, or dam building". "Among these new diseases, surprisingly, most emergent viruses and many emergent bacteria are zoonotic". Several new zoonoses have been recently identified. Many of these diseases were either unknown, because we were not able to isolate the infectious agent or to distinguish them from other clinical syndromes, or discovered accidentally. Much of the recent identification of new pathogens has been based on new molecular biology tools or epidemiological studies. For all these diseases or infections, veterinarians played a key role in their identification, isolation of the causative organisms and understanding of the epidemiology of the infection. The role of the veterinary profession is very important in public health and on the rise again in the U.S.A., as it should be in many other countries. Surveillance, clinical curiosity and awareness, epidemiology and laboratory training are the essential tools and competency that the veterinary profession must use to meet the challenge of new emerging zoonoses.

摘要

新发传染病的概念出现在20世纪80年代末,当时全球范围内发生了重大疫情,这让许多认为传染病是过去的疾病或仅限于欠发达国家的科学家感到惊讶。几份报告指出,公共卫生基础设施的薄弱是导致新出现和重新出现的传染病的因素之一。正如莫尔斯所指出的,“疾病的出现往往伴随着人类活动引起的生态变化,如农业或农业变革、移民、城市化、森林砍伐或水坝建设”。“令人惊讶的是,在这些新出现的疾病中,大多数新出现的病毒和许多新出现的细菌都是人畜共患病”。最近发现了几种新的人畜共患病。其中许多疾病要么不为人知,因为我们无法分离出传染源或将它们与其他临床综合征区分开来,要么是偶然发现的。最近对新病原体的许多鉴定都是基于新的分子生物学工具或流行病学研究。对于所有这些疾病或感染,兽医在其鉴定、致病生物的分离以及感染流行病学的理解方面发挥了关键作用。兽医行业在公共卫生中发挥着非常重要的作用,在美国正再次兴起,在许多其他国家也应该如此。监测、临床好奇心和意识、流行病学和实验室培训是兽医行业应对新出现的人畜共患病挑战必须使用的基本工具和能力。

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