肺炎克雷伯菌对小鼠和松鼠猴的给药方法与呼吸道毒力的关系。
Relationship of method of administration to respiratory virulence of Klebsiella pneumoniae for mice and squirrel monkeys.
作者信息
Berendt R F
出版信息
Infect Immun. 1978 May;20(2):581-3. doi: 10.1128/iai.20.2.581-583.1978.
Abstract
Klebsiella pneumoniae given by aerosol was significantly less virulent in mice and monkeys than when given by intranasal (mice) or intratracheal (monkeys) instillation.
摘要
通过气溶胶给予小鼠和猴子的肺炎克雷伯菌，其毒性明显低于经鼻（小鼠）或气管内（猴子）滴注给药时的毒性。
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本文引用的文献
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Nature. 1962 Nov 10;196:598-9. doi: 10.1038/196598b0.
2
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N Engl J Med. 1969 Nov 20;281(21):1137-40. doi: 10.1056/NEJM196911202812101.
3
Modified spinning top homogeneous spray apparatus for use in experimental respiratory disease studies.用于实验性呼吸道疾病研究的改良型旋转顶部均匀喷雾装置。
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