Zhang J Q, Thomas T R, Ball S D
Exercise Physiology Laboratory, Department of Food Science and Human Nutrition, University of Missouri-Columbia, Columbia, Missouri 65212, USA.
J Appl Physiol (1985). 1998 Oct;85(4):1516-22. doi: 10.1152/jappl.1998.85.4.1516.
The purpose of the study was to examine the effect of exercise timing on postprandial lipemia responses. Subjects were 21 recreationally trained men (ages 27 +/- 1.7 yr). Each subject performed four trials: 1) Control (fat meal only), 2) Post (exercise 1 h after a fat meal), 3) 1 h-Pre (exercise 1 h before a fat meal), and 4) 12 h-Pre (exercise 12 h before a fat meal). In each trial, subjects had a standard fat meal to induce postprandial hypertriglyceridemia. Blood samples were taken at 0 h (immediately before the fat meal) and at 2, 4, 6, 8, and 24 h after the meal. In the exercise trials, each subject exercised at 60% of maximal O2 consumption for 1 h. The results indicated that triglyceride area under the curve scores in premeal-exercise trials were lower (P < 0. 05) than those in Post and Control. At 24 h, total high-density lipoprotein (HDL)-cholesterol in the premeal-exercise trials was higher (P < 0.05) than that at 0 h, whereas total HDL-cholesterol was not changed in Control and Post. At 24 h, HDL subtype 2-cholesterol was higher (P < 0.05) in the premeal-exercise trials than in Control, which did not differ from Post. These results suggest that exercising before a fat meal may have a beneficial effect on the triglyceride response and HDL metabolism, which may blunt atherosclerotic process induced by the fat meal.
本研究的目的是检验运动时间对餐后血脂反应的影响。受试者为21名进行休闲锻炼的男性（年龄27±1.7岁）。每位受试者进行四项试验：1）对照（仅食用高脂餐），2）餐后（高脂餐后1小时运动），3）餐前1小时（高脂餐前1小时运动），4）餐前12小时（高脂餐前12小时运动）。在每项试验中，受试者食用标准高脂餐以诱发餐后高甘油三酯血症。在0小时（高脂餐进食前即刻）以及餐后2、4、6、8和24小时采集血样。在运动试验中，每位受试者以最大耗氧量的60%运动1小时。结果表明，餐前运动试验中甘油三酯曲线下面积得分低于餐后和对照试验（P<0.05）。在24小时时，餐前运动试验中的总高密度脂蛋白（HDL）胆固醇高于0小时时（P<0.05），而对照和餐后试验中的总HDL胆固醇没有变化。在24小时时，餐前运动试验中的HDL 2亚型胆固醇高于对照试验（P<0.05），与餐后试验无差异。这些结果表明，在高脂餐前运动可能对甘油三酯反应和HDL代谢有有益影响，这可能会减轻高脂餐诱发的动脉粥样硬化过程。
