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Microtubules and microscopes: how the development of light microscopic imaging technologies has contributed to discoveries about microtubule dynamics in living cells.微管与显微镜:光学显微镜成像技术的发展如何助力关于活细胞中微管动力学的发现。
Mol Biol Cell. 1998 Dec;9(12):3263-71. doi: 10.1091/mbc.9.12.3263.
2
Fluorescent speckle microscopy of spindle microtubule assembly and motility in living cells.活细胞中纺锤体微管组装与运动的荧光斑点显微镜观察
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Microtubule dynamics in mitotic spindle displayed by polarized light microscopy.通过偏振光显微镜观察有丝分裂纺锤体中的微管动力学。
Mol Biol Cell. 1998 Jul;9(7):1603-7. doi: 10.1091/mbc.9.7.1603.
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Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.有丝分裂纺锤体中微管向极运动:荧光光活化的证据
J Cell Biol. 1989 Aug;109(2):637-52. doi: 10.1083/jcb.109.2.637.
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Analysis of the treadmilling model during metaphase of mitosis using fluorescence redistribution after photobleaching.利用光漂白后的荧光重新分布分析有丝分裂中期的踏车模型。
J Cell Biol. 1986 Mar;102(3):1032-8. doi: 10.1083/jcb.102.3.1032.
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Super-resolution video microscopy of live cells by structured illumination.通过结构光照明显微镜对活细胞进行超分辨率视频显微镜观察。
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Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling.迁移上皮细胞片层中基于肌动球蛋白的微管逆行流动影响微管动态不稳定性和周转,并与微管断裂和踏车行为相关。
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Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms.内质网的膜性小管在活细胞中通过三种不同机制由微管分布。
Curr Biol. 1998 Jul 2;8(14):798-806. doi: 10.1016/s0960-9822(98)70321-5.
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The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work.与极向通量相关的动粒微管负端解聚产生一种能够做功的力。
Mol Biol Cell. 1996 Oct;7(10):1547-58. doi: 10.1091/mbc.7.10.1547.
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Microtubule/organelle motility assays.微管/细胞器运动分析
Curr Protoc Cell Biol. 2001 May;Chapter 13:Unit 13.1. doi: 10.1002/0471143030.cb1301s00.

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Automated segmentation and tracking of mitochondria in live-cell time-lapse images.活细胞延时成像中线粒体的自动分割和跟踪。
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Dynamics and organization of cortical microtubules as revealed by superresolution structured illumination microscopy.超分辨率结构光照明显微镜揭示的皮质微管的动力学和组织
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A minimal optical trapping and imaging microscopy system.一个最小光学捕获和成像显微镜系统。
PLoS One. 2013;8(2):e57383. doi: 10.1371/journal.pone.0057383. Epub 2013 Feb 25.
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Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway.整合素 α5β1-菌毛结合和肌动蛋白重排对于牙龈卟啉单胞菌侵入成骨细胞和随后激活 JNK 途径是必不可少的。
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Analysis of microtubule dynamics by polarized light.用偏振光分析微管动力学。
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6
AIDA: an adaptive image deconvolution algorithm with application to multi-frame and three-dimensional data.AIDA:一种适用于多帧和三维数据的自适应图像去卷积算法。
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7
Visualization and examination of the meiotic spindle in human oocytes with polscope.使用偏振显微镜观察和检测人类卵母细胞中的减数分裂纺锤体。
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Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes.蛋白激酶C激活通过延长微管平均生长寿命来促进神经元生长锥中的微管前进。
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本文引用的文献

1
Production and presentation of digital movies.数字电影的制作与展示。
Trends Cell Biol. 1997 Dec;7(12):503-6. doi: 10.1016/S0962-8924(97)01171-9.
2
Fluorescent speckle microscopy of spindle microtubule assembly and motility in living cells.活细胞中纺锤体微管组装与运动的荧光斑点显微镜观察
Methods Cell Biol. 1999;61:155-73. doi: 10.1016/s0091-679x(08)61980-9.
3
Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells.荧光斑点显微镜术,一种用于观察活细胞中蛋白质聚集体动态变化的方法。
Curr Biol. 1998 Nov 5;8(22):1227-30. doi: 10.1016/s0960-9822(07)00515-5.
4
How microtubules get fluorescent speckles.微管如何产生荧光斑点。
Biophys J. 1998 Oct;75(4):2059-69. doi: 10.1016/S0006-3495(98)77648-9.
5
The role of nucleation in patterning microtubule networks.成核在微管网络模式形成中的作用。
J Cell Sci. 1998 Aug;111 ( Pt 15):2077-83. doi: 10.1242/jcs.111.15.2077.
6
Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms.内质网的膜性小管在活细胞中通过三种不同机制由微管分布。
Curr Biol. 1998 Jul 2;8(14):798-806. doi: 10.1016/s0960-9822(98)70321-5.
7
Nuclear and spindle dynamics in budding yeast.芽殖酵母中的细胞核与纺锤体动力学
Mol Biol Cell. 1998 Jul;9(7):1627-31. doi: 10.1091/mbc.9.7.1627.
8
Microtubule dynamics in mitotic spindle displayed by polarized light microscopy.通过偏振光显微镜观察有丝分裂纺锤体中的微管动力学。
Mol Biol Cell. 1998 Jul;9(7):1603-7. doi: 10.1091/mbc.9.7.1603.
9
Digital deconvolution of fluorescence images for biologists.面向生物学家的荧光图像数字反卷积
Methods Cell Biol. 1998;56:305-15. doi: 10.1016/s0091-679x(08)60432-x.
10
A high-resolution multimode digital microscope system.一种高分辨率多模式数字显微镜系统。
Methods Cell Biol. 1998;56:185-215.

Microtubules and microscopes: how the development of light microscopic imaging technologies has contributed to discoveries about microtubule dynamics in living cells.

作者信息

Waterman-Storer C M

机构信息

Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599-3280, USA.

出版信息

Mol Biol Cell. 1998 Dec;9(12):3263-71. doi: 10.1091/mbc.9.12.3263.

DOI:10.1091/mbc.9.12.3263
PMID:9843568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC25623/
Abstract
摘要