抗巨细胞病毒（抗CMV）免疫球蛋白G亲和力在识别有传播先天性CMV感染风险的孕妇中的作用。
Anticytomegalovirus (anti-CMV) immunoglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection.
作者信息
Lazzarotto T, Spezzacatena P, Varani S, Gabrielli L, Pradelli P, Guerra B, Landini M P
机构信息
Department of Clinical and Experimental Medicine, Section of Microbiology, Medical School, University of Bologna, Bologna, Italy.
出版信息
Clin Diagn Lab Immunol. 1999 Jan;6(1):127-9. doi: 10.1128/CDLI.6.1.127-129.1999.
Abstract
In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.
摘要
在本研究中，我们表明，在妊娠18周前进行抗巨细胞病毒抗体亲和力测定是一种有助于确定纳入产前诊断的孕妇的工具。该程序可以识别所有将分娩出受感染新生儿的孕妇。
相似文献
1
Anticytomegalovirus (anti-CMV) immunoglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection.抗巨细胞病毒（抗CMV）免疫球蛋白G亲和力在识别有传播先天性CMV感染风险的孕妇中的作用。
Clin Diagn Lab Immunol. 1999 Jan;6(1):127-9. doi: 10.1128/CDLI.6.1.127-129.1999.
2
Maternal IgG avidity and IgM detected by blot as diagnostic tools to identify pregnant women at risk of transmitting cytomegalovirus.通过印迹法检测母体IgG亲和力和IgM作为诊断工具，以识别有传播巨细胞病毒风险的孕妇。
Viral Immunol. 2000;13(1):137-41. doi: 10.1089/vim.2000.13.137.
3
Strong Cell-Mediated Immune Response to Human Cytomegalovirus Is Associated With Increased Risk of Fetal Infection in Primarily Infected Pregnant Women.原发性感染孕妇的强烈细胞免疫反应与胎儿感染风险增加相关。
Clin Infect Dis. 2015 Oct 15;61(8):1228-34. doi: 10.1093/cid/civ561. Epub 2015 Jul 14.
4
Screening, diagnosis, and management of cytomegalovirus infection in pregnancy.妊娠期巨细胞病毒感染的筛查、诊断和处理。
Obstet Gynecol Surv. 2010 Nov;65(11):736-43. doi: 10.1097/OGX.0b013e31821102b4.
5
New advances in the diagnosis of congenital cytomegalovirus infection.先天性巨细胞病毒感染诊断的新进展
J Clin Virol. 2008 Mar;41(3):192-7. doi: 10.1016/j.jcv.2007.10.015. Epub 2007 Dec 4.
6
New developments in the diagnosis of maternal and congenital CMV infection.母婴及先天性巨细胞病毒感染诊断的新进展。
Expert Rev Mol Diagn. 2001 May;1(1):19-29. doi: 10.1586/14737159.1.1.19.
7
New advances in the diagnosis of congenital cytomegalovirus infection.
Intervirology. 1999;42(5-6):390-7. doi: 10.1159/000053976.
8
The IgG avidity value for the prediction of congenital cytomegalovirus infection in a prospective cohort study.在一项前瞻性队列研究中，用于预测先天性巨细胞病毒感染的IgG亲和力值。
J Perinat Med. 2014 Nov;42(6):755-9. doi: 10.1515/jpm-2013-0333.
9
Reconsideration of Maternal Serological Testing for Predicting Congenital CMV Infection.重新考虑母体血清学检测在预测先天性 CMV 感染中的作用。
J Infect Dis. 2024 Jun 14;229(6):1817-1822. doi: 10.1093/infdis/jiad412.
10
Prenatal diagnosis of congenital cytomegalovirus infection in 189 pregnancies with known outcome.189例已知妊娠结局的先天性巨细胞病毒感染的产前诊断
Prenat Diagn. 2001 May;21(5):362-77. doi: 10.1002/pd.59.
引用本文的文献
1
Reliability of CMV-IgG kinetics in the diagnosis of CMV primary infection: sensitivity, specificity, and clinical implications.巨细胞病毒IgG动力学在巨细胞病毒原发性感染诊断中的可靠性：敏感性、特异性及临床意义。
Microbiol Spectr. 2025 Aug 5;13(8):e0045525. doi: 10.1128/spectrum.00455-25. Epub 2025 Jun 17.
2
Hygiene promotion might be better than serological screening to deal with Cytomegalovirus infection during pregnancy: a methodological appraisal and decision analysis.卫生促进可能比血清学筛查更能处理怀孕期间巨细胞病毒感染：方法学评估和决策分析。
BMC Infect Dis. 2020 Jun 16;20(1):418. doi: 10.1186/s12879-020-05139-8.
3
Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery.在CD4 + T细胞免疫恢复不佳的HIV感染者中，对巨细胞病毒的体液反应增强。
PLoS One. 2017 Sep 21;12(9):e0184433. doi: 10.1371/journal.pone.0184433. eCollection 2017.
4
Severe neonatal cytomegalovirus infection: about a case.严重新生儿巨细胞病毒感染：病例报告
Pan Afr Med J. 2017 Jun 30;27:161. doi: 10.11604/pamj.2017.27.161.12004. eCollection 2017.
5
Testing for Cytomegalovirus in Pregnancy.孕期巨细胞病毒检测
J Clin Microbiol. 2017 Mar;55(3):693-702. doi: 10.1128/JCM.01868-16. Epub 2016 Dec 28.
6
Seroprevalence of cytomegalovirus among pregnant women attending Murtala Mohammed Specialist Hospital Kano, Nigeria.尼日利亚卡诺市穆尔塔拉·穆罕默德专科医院就诊孕妇中巨细胞病毒的血清流行率。
Afr Health Sci. 2014 Mar;14(1):125-30. doi: 10.4314/ahs.v14i1.19.
7
Role of cytomegalovirus (CMV) IgG avidity testing in diagnosing primary CMV infection during pregnancy.巨细胞病毒（CMV）IgG亲和力检测在诊断孕期原发性巨细胞病毒感染中的作用。
Clin Vaccine Immunol. 2014 Oct;21(10):1377-84. doi: 10.1128/CVI.00487-14. Epub 2014 Aug 27.
8
Comment on the paper by Kamel et al. Entitled 'Primary cytomegalovirus infection in pregnant Egyptian women confirmed by cytomegalovirus IgG avidity testing'.对卡迈勒等人所著论文《通过巨细胞病毒IgG亲和力检测确诊的埃及孕妇原发性巨细胞病毒感染》的评论
Med Princ Pract. 2015;24(1):101. doi: 10.1159/000365446. Epub 2014 Aug 14.
9
The role of maternal screening in diagnosing congenital cytomegalovirus infections in highly immune populations.母体筛查在高度免疫人群先天性巨细胞病毒感染诊断中的作用。
Ir J Med Sci. 2015 Jun;184(2):475-81. doi: 10.1007/s11845-014-1149-5. Epub 2014 Jun 4.
10
Analytical issues possibly affecting the performance of commercial human cytomegalovirus IgG avidity assays.可能影响商业人巨细胞病毒 IgG 亲和力检测试剂盒性能的分析问题。
Eur J Clin Microbiol Infect Dis. 2014 Sep;33(9):1579-84. doi: 10.1007/s10096-014-2109-8. Epub 2014 Apr 30.
本文引用的文献
1
Prenatal diagnosis of congenital cytomegalovirus infection.先天性巨细胞病毒感染的产前诊断
J Clin Microbiol. 1998 Dec;36(12):3540-4. doi: 10.1128/JCM.36.12.3540-3544.1998.
2
Avidity of immunoglobulin G directed against human cytomegalovirus during primary and secondary infections in immunocompetent and immunocompromised subjects.免疫功能正常和免疫功能低下受试者在原发性和继发性感染期间针对人巨细胞病毒的免疫球蛋白G亲和力
Clin Diagn Lab Immunol. 1997 Jul;4(4):469-73. doi: 10.1128/cdli.4.4.469-473.1997.
3
Treatment of viral infections during pregnancy and the neonatal period.孕期及新生儿期病毒感染的治疗。
Clin Perinatol. 1997 Mar;24(1):267-83.
4
Value of cytomegalovirus (CMV) IgG avidity index for the diagnosis of primary CMV infection in pregnant women.巨细胞病毒（CMV）IgG亲和力指数在诊断孕妇原发性巨细胞病毒感染中的价值。
J Infect Dis. 1997 Apr;175(4):944-6. doi: 10.1086/513996.
5
Evaluation of virological procedures to detect fetal human cytomegalovirus infection: avidity of IgG antibodies, virus detection in amniotic fluid and maternal serum.检测胎儿人巨细胞病毒感染的病毒学方法评估：IgG抗体亲和力、羊水和母血清中的病毒检测
J Med Virol. 1996 Sep;50(1):9-15. doi: 10.1002/(SICI)1096-9071(199609)50:1<9::AID-JMV3>3.0.CO;2-5.
6
IgM antibody detection of ppUL80A and ppUL32 by immunoblotting: an early parameter for recurrent cytomegalovirus infection in renal transplant recipients.通过免疫印迹法检测ppUL80A和ppUL32的IgM抗体：肾移植受者复发性巨细胞病毒感染的早期指标
J Med Virol. 1996 Mar;48(3):289-94. doi: 10.1002/(SICI)1096-9071(199603)48:3<289::AID-JMV13>3.0.CO;2-8.
7
Polymerase chain reaction for prenatal diagnosis of congenital human cytomegalovirus infection.用于先天性人巨细胞病毒感染产前诊断的聚合酶链反应
J Med Virol. 1995 Dec;47(4):462-6. doi: 10.1002/jmv.1890470428.
8
Maturation of antibody avidity after primary human cytomegalovirus infection is delayed in immunosuppressed solid organ transplant patients.在免疫抑制的实体器官移植患者中，原发性人巨细胞病毒感染后抗体亲和力的成熟会延迟。
J Med Virol. 1994 Dec;44(4):317-22. doi: 10.1002/jmv.1890440402.
9
Accuracy of amniotic fluid testing before 21 weeks' gestation in prenatal diagnosis of congenital cytomegalovirus infection.
Prenat Diagn. 1994 Nov;14(11):1055-9. doi: 10.1002/pd.1970141108.
10
Congenital cytomegalovirus infection: The relative importance of primary and recurrent maternal infection.先天性巨细胞病毒感染：母体原发性感染和复发性感染的相对重要性
N Engl J Med. 1982 Apr 22;306(16):945-9. doi: 10.1056/NEJM198204223061601.
Zotero 插件