D'Lima D D, Lemperle S M, Chen P C, Holmes R E, Colwell C W
Division of Orthopaedic Surgery, Scripps Clinic and Research Foundation, La Jolla, California 92037, USA.
J Arthroplasty. 1998 Dec;13(8):928-34. doi: 10.1016/s0883-5403(98)90201-7.
This study was designed to measure implant osseointegration using different surface treatments. Bilateral distal intramedullary implantation of titanium cylinders 25 mm x 5 mm was performed in 60 rabbits. The 3 surfaces tested were fiber mesh, mean pore size 400 microns; grit-blasted, mean surface roughness 6 microns; and acid-etched, mean surface roughness 18 microns. Scanning electron microscopy was used to measure the percentage of the surface of each implant in contact with bone at 2, 6, and 12 weeks postimplantation. Mechanical pull-out testing of the bone-implant interface was performed at 12 weeks. Overall, acid-etched surfaces demonstrated greater mean osseointegration than fiber mesh surfaces. All 3 surfaces demonstrated similar interface strengths. Acid etching has potential as a means of enhancing bony apposition in cementless fixation.
本研究旨在使用不同的表面处理方法来测量种植体的骨结合情况。对60只兔子进行双侧远端髓内植入25毫米×5毫米的钛圆柱体。测试的3种表面分别是纤维网，平均孔径400微米；喷砂处理，平均表面粗糙度6微米；以及酸蚀处理，平均表面粗糙度18微米。使用扫描电子显微镜来测量植入后2周、6周和12周时每个种植体与骨接触的表面百分比。在12周时对骨-种植体界面进行机械拔出测试。总体而言，酸蚀表面显示出比纤维网表面更高的平均骨结合。所有3种表面都显示出相似的界面强度。酸蚀作为一种增强非骨水泥固定中骨附着的方法具有潜力。
