Juniper E F
Department of Clinical Epidemiology and Biostatistics, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada.
Pharmacoeconomics. 1995 Aug;8(2):123-38. doi: 10.2165/00019053-199508020-00004.
There is a growing body of evidence showing that the conventional clinical indices of asthma severity (airway calibre, symptoms, airway responsiveness, etc.) correlate only weakly with how patients are actually feeling and how they are able to function in their daily lives because of their asthma. When assessing and treating asthma, it is certainly important to evaluate the airways. However, it is equally important to evaluate the impact of the condition on the patients themselves. There are now a number of health-related quality-of-life instruments, with strong measurement properties, that may be used in both clinical studies and practice. They provide scientifically sound and valid information about patients' experience that complements conventional clinical measures.
越来越多的证据表明,哮喘严重程度的传统临床指标(气道口径、症状、气道反应性等)与患者的实际感受以及因哮喘而在日常生活中的功能状态之间的相关性很弱。在评估和治疗哮喘时,评估气道固然重要。然而,评估该疾病对患者自身的影响同样重要。现在有许多具有强大测量属性的与健康相关的生活质量工具,可用于临床研究和实践。它们提供了关于患者体验的科学合理且有效的信息,对传统临床测量起到补充作用。