Juniper E F
Department of Clinical Epidemiology and Biostatistics, McMaster University Medical Centre, Hamilton, Ontario, Canada.
Allergy. 1997 Oct;52(10):971-7. doi: 10.1111/j.1398-9995.1997.tb02416.x.
Many clinicians now recognize the importance of incorporating an assessment of health-related quality of life (HRQL) into their clinical studies and practice. Conventional clinical measures provide valuable information about the status of the affected organ system, but they rarely capture the functional impairments (physical, emotional, and social) that are important to the patients in their everyday lives. In order to obtain a complete picture of a patient's health status, both the conventional clinical indices and the patient's HRQL must be measured. Both adults and children with asthma and rhinitis are distressed by the symptoms, and they are limited in their day-to-day activities such as sports, work or school work, and participation in other activities with friends. In addition, both adults and children experience emotional strain as a result of both conditions. Disease-specific HRQL questionnaires have been developed and validated for both adults and children with asthma and rhinitis. These questionnaires have good measurement properties and validity and can be used in both clinical trials and clinical practice to assess the impact of the condition on a patient's life. Since one of the aims of treatment is to ensure that patients benefit from it, an essential component of clinical assessment should be an evaluation of HRQL.
现在许多临床医生认识到将健康相关生活质量(HRQL)评估纳入其临床研究和实践的重要性。传统的临床测量方法能提供有关受影响器官系统状况的有价值信息,但它们很少能捕捉到对患者日常生活很重要的功能障碍(身体、情感和社交方面)。为了全面了解患者的健康状况,必须同时测量传统临床指标和患者的HRQL。患有哮喘和鼻炎的成人和儿童都会因症状而苦恼,他们在日常活动中受到限制,如运动、工作或学业,以及参与和朋友的其他活动。此外,成人和儿童都会因这两种病症而经历情绪紧张。针对患有哮喘和鼻炎的成人和儿童,已经开发并验证了特定疾病的HRQL问卷。这些问卷具有良好的测量特性和效度,可用于临床试验和临床实践,以评估病症对患者生活的影响。由于治疗的目标之一是确保患者从中受益,临床评估的一个重要组成部分应该是对HRQL的评估。