人类红细胞衰老过程中细胞膜碳水化合物含量的变化。
Changes in carbohydrate content of surface membranes of human erythrocytes during ageing.
作者信息
Gattegno L, Bladier D, Garnier M, Cornillot P
出版信息
Carbohydr Res. 1976 Dec;52:197-208. doi: 10.1016/s0008-6215(00)85960-1.
PMID:1016988
Abstract
The carbohydrate content (neutral hexoses, fucose, sialic acid, and hexosamine) of human erythrocytes is significantly higher in young than in old erythrocytes. The differences observed in the carbohydrate content of surface glycopeptides, obtained after incubation with either Pronase or trypsin, is still more striking, suggesting important modifications of the carbohydrate moeties of the erythrocyte membrane during in vivo ageing.
摘要
人类红细胞的碳水化合物含量（中性己糖、岩藻糖、唾液酸和氨基己糖）在年轻红细胞中显著高于老年红细胞。在用链霉蛋白酶或胰蛋白酶孵育后获得的表面糖肽的碳水化合物含量差异更为显著，这表明在体内老化过程中红细胞膜的碳水化合物部分发生了重要变化。
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