Faulkner P M, Weary D M
Animal Welfare Program, Faculty of Agricultural Sciences and Centre for Applied Ethics, University of British Columbia, Vancouver, Canada.
J Dairy Sci. 2000 Sep;83(9):2037-41. doi: 10.3168/jds.S0022-0302(00)75084-3.
We investigated behavioral responses after dehorning and a sham procedure in 20 Holstein calves aged 4 to 8 wk. Calves either received a nonsteroidal antiinflammatory drug (ketoprofen) before dehorning as well as 2 and 7 h after the procedure or were assigned to a control group. All calves received a sedative (xylazine) and local anaesthetic (lidocaine) before dehorning, and responses were scored over 24 h after the procedure. After hot-iron dehorning, calves treated with ketoprofen also demonstrated little head shaking or ear flicking, but control animals demonstrated higher frequencies of these behaviors; both responses peaked 6 h after dehorning. Differences between the treatment groups remained statistically significant until 12 h (head shaking) and 24 h (ear flicking) after dehorning. A low frequency of head rubbing was observed in both treatment groups, but control calves were more frequently observed engaged in this behavior. There was no statistically significant effect of treatment on any of the other behavioral measures. Calves treated with ketoprofen also tended to gain more weight (1.2+/-0.4 kg) during the 24 h after dehorning than did control calves (0.2+/-0.4 kg). There was no effect of treatment on any of the response variables when calves were sham dehorned. These results indicate that ketoprofen mitigates pain after hot-iron dehorning in young dairy calves.
我们研究了20头4至8周龄荷斯坦犊牛去角和假手术操作后的行为反应。犊牛在去角前以及术后2小时和7小时，要么接受非甾体抗炎药（酮洛芬）治疗，要么被分配到对照组。所有犊牛在去角前均接受镇静剂（赛拉嗪）和局部麻醉剂（利多卡因），并在术后24小时对反应进行评分。热烙铁去角后，接受酮洛芬治疗的犊牛摇头或甩耳的情况也较少，但对照动物的这些行为频率更高；两种反应均在去角后6小时达到峰值。治疗组之间的差异在去角后12小时（摇头）和24小时（甩耳）之前一直具有统计学意义。在两个治疗组中均观察到低频率的蹭头行为，但对照犊牛出现这种行为的频率更高。治疗对任何其他行为指标均无统计学显著影响。与对照犊牛（0.2±0.4千克）相比，接受酮洛芬治疗的犊牛在去角后24小时内体重增加也更多（1.2±0.4千克）。对犊牛进行假去角时，治疗对任何反应变量均无影响。这些结果表明，酮洛芬可减轻幼龄奶牛犊牛热烙铁去角后的疼痛。
