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Correlation of human immunodeficiency virus type 1 RNA levels in blood and the female genital tract.血液与女性生殖道中1型人类免疫缺陷病毒RNA水平的相关性
J Infect Dis. 1999 Apr;179(4):871-82. doi: 10.1086/314656.
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Cervical human immunodeficiency virus type 1 shedding is associated with genital beta-chemokine secretion.
J Infect Dis. 1998 Nov;178(5):1334-42. doi: 10.1086/314433.
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Distinct determinants of human immunodeficiency virus type 1 RNA and DNA loads in vaginal and cervical secretions.1型人类免疫缺陷病毒在阴道和宫颈分泌物中RNA和DNA载量的不同决定因素。
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Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood.精液中可培养的1型人类免疫缺陷病毒(HIV-1)与精液及血液中HIV-1 RNA水平之间的关联:HIV-1在精液和血液之间存在区室化的证据
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HIV-1 detection in cervicovaginal secretions during pregnancy.孕期宫颈阴道分泌物中的HIV-1检测
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Presence of cell-free human immunodeficiency virus in cervicovaginal secretions is independent of viral load in the blood of human immunodeficiency virus-infected women.人免疫缺陷病毒感染女性的宫颈阴道分泌物中游离人免疫缺陷病毒的存在与血液中的病毒载量无关。
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Detection of HIV DNA in cervical and vaginal secretions. Prevalence and correlates among women in Nairobi, Kenya.检测宫颈和阴道分泌物中的HIV DNA。肯尼亚内罗毕女性中的患病率及相关因素。
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Virus excretion in the cervicovaginal secretions of pregnant and nonpregnant HIV-infected women.怀孕和未怀孕的HIV感染女性宫颈阴道分泌物中的病毒排泄情况。
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女性生殖道中1型人类免疫缺陷病毒的检测与定量。艾滋病治疗研究倡议009研究组。

Detection and quantitation of human immunodeficiency virus type 1 in the female genital tract. The Division of AIDS Treatment Research Initiative 009 Study Group.

作者信息

Baron P, Bremer J, Wasserman S S, Nowicki M, Driscoll B, Polsky B, Kovacs A, Reichelderfer P S

机构信息

St. Luke's Hospital, New York, New York 10025, USA.

出版信息

J Clin Microbiol. 2000 Oct;38(10):3822-4. doi: 10.1128/JCM.38.10.3822-3824.2000.

DOI:10.1128/JCM.38.10.3822-3824.2000
PMID:11015409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC87482/
Abstract

Human immunodeficiency virus type 1 (HIV-1) was detected in the genital tracts of 59% of 225 women by RNA PCR and in 7% of the women by culture. In a comparison of two sampling methods, endocervical swabs were more sensitive than cervicovaginal lavage for HIV-1 RNA detection by PCR but not by culture and their sensitivity was independent of the concentration of HIV-1 RNA.

摘要

通过RNA聚合酶链反应(PCR)在225名女性中的59%的生殖道中检测到了1型人类免疫缺陷病毒(HIV-1),通过培养在7%的女性中检测到了该病毒。在两种采样方法的比较中,对于通过PCR检测HIV-1 RNA而言,宫颈拭子比宫颈阴道灌洗更敏感,但对于培养检测则不然,并且它们的敏感性与HIV-1 RNA的浓度无关。