女性生殖道中1型人类免疫缺陷病毒的检测与定量。艾滋病治疗研究倡议009研究组。
Detection and quantitation of human immunodeficiency virus type 1 in the female genital tract. The Division of AIDS Treatment Research Initiative 009 Study Group.
作者信息
Baron P, Bremer J, Wasserman S S, Nowicki M, Driscoll B, Polsky B, Kovacs A, Reichelderfer P S
机构信息
St. Luke's Hospital, New York, New York 10025, USA.
出版信息
J Clin Microbiol. 2000 Oct;38(10):3822-4. doi: 10.1128/JCM.38.10.3822-3824.2000.
Abstract
Human immunodeficiency virus type 1 (HIV-1) was detected in the genital tracts of 59% of 225 women by RNA PCR and in 7% of the women by culture. In a comparison of two sampling methods, endocervical swabs were more sensitive than cervicovaginal lavage for HIV-1 RNA detection by PCR but not by culture and their sensitivity was independent of the concentration of HIV-1 RNA.
摘要
通过RNA聚合酶链反应（PCR）在225名女性中的59%的生殖道中检测到了1型人类免疫缺陷病毒（HIV-1），通过培养在7%的女性中检测到了该病毒。在两种采样方法的比较中，对于通过PCR检测HIV-1 RNA而言，宫颈拭子比宫颈阴道灌洗更敏感，但对于培养检测则不然，并且它们的敏感性与HIV-1 RNA的浓度无关。
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