Michelson H, Bolund C, Nilsson B, Brandberg Y
Department of Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
Acta Oncol. 2000;39(4):477-84. doi: 10.1080/028418600750013384.
The EORTC QLQ-C30 Health-Related Quality of Life (HRQOL) questionnaire was completed by 3069/3919 (78%) of a random sample of the Swedish population aged 18-79 years. The aims of the study were to provide normative data on the questionnaire and to investigate differences in HRQOL with respect to age, gender, sociodemographic characteristics and reported chronic health problems. Women had lower scores than men on all but one of the EORTC QLQ-C30 subscales and reported more chronic health problems. The oldest respondents (70-79 years) had a greater degree of impaired HRQOL than the other age groups, with one exception, 'Emotional functioning', in which they scored higher. Unemployed respondents reported poorer HRQOL than employed respondents. Higher income was associated with a more positive assessment of HRQOL. The results of the study present reference values for EORTC QLQ-C30 Version 3 questionnaire and clarify the influence of factors which should be taken into account when planning studies of HRQOL.
18至79岁的瑞典随机抽样人群中，3069人（占3919人的78%）完成了欧洲癌症研究与治疗组织（EORTC）的QLQ-C30健康相关生活质量（HRQOL）问卷。该研究的目的是提供该问卷的规范数据，并调查HRQOL在年龄、性别、社会人口学特征和报告的慢性健康问题方面的差异。在EORTC QLQ-C30的所有子量表中，除了一个子量表外，女性的得分均低于男性，且报告的慢性健康问题更多。年龄最大的受访者（70 - 79岁）的HRQOL受损程度比其他年龄组更大，但“情感功能”这一项除外，在该项中他们得分更高。失业受访者报告的HRQOL比就业受访者更差。收入越高，对HRQOL的评价越积极。该研究结果给出了EORTC QLQ-C30第3版问卷的参考值，并阐明了在规划HRQOL研究时应考虑的因素的影响。
