一种用于检测乙型肝炎表面抗原的新型反向被动血凝试验。

A new reversed passive hemagglutination test for detection of HBsAg.

作者信息

Prince A M, Ikram H, Chicot D, Wright R, Vnek J, Neurath R, Lippin A, Swiss S

出版信息

Vox Sang. 1975;29(5):319-29. doi: 10.1111/j.1423-0410.1975.tb00516.x.

DOI:10.1111/j.1423-0410.1975.tb00516.x

Abstract

A new reversed passive hemagglutination test for HBsAg, termed Raphadex B, has been developed using immunochemically purified chimpanzee anti-HBs bound to stabilized human erythrocytes. The test has been found to have equivalent sensitivity to the Ausria 125I radioimmunoassay, and detected a similar number of HBsAg-containing specimens in screening of volunteer blood donors. This method offers an economical approach to third generation methodology for hepatitis B screening of blood donors.

摘要

一种名为Raphadex B的新型乙肝表面抗原反向被动血凝试验已被研发出来，该试验使用免疫化学纯化的黑猩猩抗乙肝表面抗体结合到稳定的人红细胞上。已发现该试验与Ausria 125I放射免疫测定法具有同等的灵敏度，并且在对志愿献血者进行筛查时检测到的含乙肝表面抗原标本数量相似。这种方法为献血者乙肝筛查的第三代方法提供了一种经济的途径。