Puder C, Loya S, Hizi A, Zeeck A
Institut für Organische Chemie, Universität Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany.
J Nat Prod. 2001 Jan;64(1):42-5. doi: 10.1021/np000377i.
Variation of the culture conditions of Streptomyces sp. strain A1, which produces streptazolin (1), resulted in the isolation of four new co-metabolites: 5-O-(beta-D-xylopyranosyl)streptazolin (3), 9-hydroxystreptazolin (4), 13-hydroxystreptazolin (5), and streptenol E (6). Their structures were established by spectroscopic and chemical methods. The possible biosynthetic relationship between the streptazolins and the streptenols is discussed.
产生链唑啉（1）的链霉菌属菌株A1培养条件的变化，导致分离出四种新的共代谢产物：5-O-（β-D-吡喃木糖基）链唑啉（3）、9-羟基链唑啉（4）、13-羟基链唑啉（5）和链烯醇E（6）。通过光谱和化学方法确定了它们的结构。讨论了链唑啉类化合物和链烯醇类化合物之间可能的生物合成关系。
