慢性酒精使用者的染色体损伤。
Chromosomal damage in chronic alcohol users.
作者信息
Obe G, Herha J
出版信息
Humangenetik. 1975 Sep 23;29(3):191-200. doi: 10.1007/BF00297623.
PMID:1165099
Abstract
First in vitro mitoses were analysed from the peripheral leukocytes of 22 chronic alcohol users and of 18 controls. The frequency of exchange aberrations of the chromatid and chromosome type were significantly higher in the alcohol as compared with the control group. The results indicate an indirect or direct mutagenic activity of alcohol in vivo.
摘要
首先对22名慢性酒精使用者和18名对照者的外周血白细胞进行体外有丝分裂分析。与对照组相比，酒精组染色单体和染色体型交换畸变的频率显著更高。结果表明酒精在体内具有间接或直接的诱变活性。
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