Karaman I, Sahin F, Güllüce M, Ogütçü H, Sengül M, Adigüzel A
Department of Biology, Faculty of Science, Gebze Institute of Technology, Kocaeli, 41400, Turkey.
J Ethnopharmacol. 2003 Apr;85(2-3):231-5. doi: 10.1016/s0378-8741(03)00006-0.
Aqueous and methanol extracts of the leaves of Juniperus oxycedrus were investigated for their in vitro antimicrobial properties. The plant was collected from Pelitli Village of Gebze, Kocaeli, in the Marmara region of Turkey. Juniperus oxycedrus is widely used as traditional folk medicine in Turkey for treatment of different infectious diseases. The antimicrobial activity of the extracts against 143 laboratory strains belonging to 56 bacterial species, and 31 isolates of 5 fungi species were evaluated based on the inhibition zone using the disc-diffusion assay, minimal inhibition concentration (MIC) and minimal bactericidal concentration (MBC) values. The aqueous extract of J. oxycedrus had no antimicrobial effect against the test microorganisms whereas the methanol extract had inhibitory effects on the growth of 57 strains of 24 bacterial species in the genera of Acinetobacter, Bacillus, Brevundimonas, Brucella, Enterobacter, Escherichia, Micrococcus, Pseudomonas, Staphylococcus, and Xanthomonas. In addition 11 Candida albicans isolates at a concentration of 31.25-250 micro g/ml were also inhibited.
对刺柏叶的水提取物和甲醇提取物的体外抗菌特性进行了研究。该植物采自土耳其马尔马拉地区科贾埃利省盖布泽的佩利特利村。在土耳其，刺柏被广泛用作治疗各种传染病的传统民间药物。基于纸片扩散法的抑菌圈、最低抑菌浓度（MIC）和最低杀菌浓度（MBC）值，评估了提取物对属于56种细菌的143株实验室菌株以及5种真菌的31个分离株的抗菌活性。刺柏水提取物对测试微生物没有抗菌作用，而甲醇提取物对不动杆菌属、芽孢杆菌属、短波单胞菌属、布鲁氏菌属、肠杆菌属、大肠杆菌属、微球菌属、假单胞菌属、葡萄球菌属和黄单胞菌属中24种细菌的57株菌株的生长有抑制作用。此外，浓度为31.25 - 250微克/毫升的11株白色念珠菌分离株也受到抑制。
