Baeumner Antje J
Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA.
Anal Bioanal Chem. 2003 Oct;377(3):434-45. doi: 10.1007/s00216-003-2158-9. Epub 2003 Aug 12.
This review article provides an overview of the most recent literature on biosensors for environmental pollutants and food contaminants. Due to the large number of publications, only papers published between 2000 and January 2003 were considered. Also, while not all of the published literature could be reviewed here, over 200 references are cited to provide a good overview of research undertaken in the last two years. Older publications are covered by a number of earlier review articles. This article provides an introduction into the field including specific consideration of the application areas, describes the typical biosensor assay format used, and is subsequently structured according to the biorecognition elements used (i.e., nucleic acids, enzymes, whole cells, tissue and whole organisms, antibodies and receptors, and biomimetic materials). In addition, a section on microbiosensing systems is provided. Since only very few microbiosensors with applications in environmental and food systems have been published, enabling technology is also covered in this article.
这篇综述文章概述了有关环境污染物和食品污染物生物传感器的最新文献。由于出版物数量众多,仅考虑了2000年至2003年1月期间发表的论文。此外,虽然无法在此处对所有已发表的文献进行综述,但引用了200多篇参考文献,以全面介绍过去两年的研究情况。较早的综述文章涵盖了更早的出版物。本文对该领域进行了介绍,包括对应用领域的具体考虑,描述了所使用的典型生物传感器检测形式,随后根据所使用的生物识别元件(即核酸、酶、全细胞、组织和全生物体、抗体和受体以及仿生材料)进行组织架构。此外,还提供了一节关于微生物传感系统的内容。由于在环境和食品系统中应用的微生物传感器发表得很少,本文还涵盖了相关的使能技术。