Khandurina Julia, Guttman András
Torrey Mesa Research Institute, 3115 Merryfield Row, San Diego, CA 92121, USA.
Curr Opin Chem Biol. 2002 Jun;6(3):359-66. doi: 10.1016/s1367-5931(02)00323-x.
In recent years, there have been significant advances in biochemical assay miniturization and integration of microchip-based technologies with combinatorial library screening for high-throughput and large-scale applications. Small-molecule microarrays, protein arrays and cell-based arrays and conventional DNA arrays as well as microfluidic approaches in HTS are discussed in this review.