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乳腺癌中的人乳头瘤病毒

Human papillomavirus in breast cancer.

作者信息

Di Lonardo A, Venuti A, Marcante M L

机构信息

Regina Elena Institute for Cancer Research, CRS, Rome, Italy.

出版信息

Breast Cancer Res Treat. 1992;21(2):95-100. doi: 10.1007/BF01836955.

DOI:10.1007/BF01836955
PMID:1320958
Abstract

Histological sections from paraffin-embedded breast carcinoma and axillary lymph nodes were examined for the presence of human papillomaviruses by two different techniques: the polymerase chain reaction (PCR) and the in situ hybridization with biotin-labelled probes. By PCR we detected HPV 16 DNA sequences in 29.4% of breast tumours and in some metastatic lymph nodes, though we were unable to identify any HPV DNA sequences by in situ hybridization. These results suggest that HPV's could play a role in the genesis of breast neoplasia.

摘要

通过两种不同技术检测石蜡包埋的乳腺癌组织切片和腋窝淋巴结中是否存在人乳头瘤病毒

聚合酶链反应（PCR）和生物素标记探针的原位杂交。通过PCR，我们在29.4%的乳腺肿瘤和一些转移性淋巴结中检测到HPV 16 DNA序列，尽管我们通过原位杂交未能鉴定出任何HPV DNA序列。这些结果表明，人乳头瘤病毒可能在乳腺肿瘤的发生中起作用。

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A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.一种新型乳头瘤病毒DNA，其在生殖器癌活检组织及源自宫颈癌的细胞系中的存在情况。
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A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.一种来自宫颈癌的乳头瘤病毒DNA及其在不同地理区域癌症活检样本中的流行情况。
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Demonstration of human papillomavirus types in paraffin processed tissue from human ano-genital lesions by in-situ DNA hybridisation.
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The prevalence of varicella zoster virus, herpes simplex virus type 2, and human papillomavirus in breast cancerous tissues and their adjacent ones in Iran.伊朗乳腺癌组织及其相邻组织中水痘带状疱疹病毒、单纯疱疹病毒2型和人乳头瘤病毒的流行情况。
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An updated systemic review and meta-analysis on human papillomavirus in breast carcinogenesis.关于人乳头瘤病毒在乳腺癌发生中的最新系统评价和荟萃分析。
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HPV-associated cancers: insights into the mechanistic scenario and latest updates.人乳头瘤病毒相关性癌症：对发病机制的深入了解和最新进展。
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HPV-Associated Breast Cancer: Myth or Fact?人乳头瘤病毒相关的乳腺癌：虚构还是事实？
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Detection of High-Risk Human Papillomavirus DNA in Invasive Ductal Carcinoma Specimens.检测浸润性导管癌标本中的高危型人乳头瘤病毒 DNA。
Asian Pac J Cancer Prev. 2022 Sep 1;23(9):3201-3207. doi: 10.31557/APJCP.2022.23.9.3201.
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J Microbiol Biotechnol. 2022 Sep 28;32(9):1086-1097. doi: 10.4014/jmb.2208.08002. Epub 2022 Aug 19.
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