Wentworth David E, Gillim-Ross Laura, Espina Noel, Bernard Kristen A
New York Department of Health, Albany 12201-2002, USA.
Emerg Infect Dis. 2004 Jul;10(7):1293-6. doi: 10.3201/eid1007.031119.
Murine models of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) will greatly advance research on this emerging virus. When BALB/c mice were simultaneously inoculated intranasally and orally, replication of SARS-CoV was found in both lung and intestinal tissue.
严重急性呼吸综合征相关冠状病毒（SARS-CoV）的小鼠模型将极大地推动对这种新出现病毒的研究。当对BALB/c小鼠进行鼻内和口服同时接种时，在肺组织和肠道组织中均发现了SARS-CoV的复制。
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