Alvarez Maria Inés, González Luz Angela, Castro Luz Angela
Facultad de Salud, Universidad del Valle, Cali, Colombia.
Mycopathologia. 2004 Aug;158(2):181-6. doi: 10.1023/b:myco.0000041866.85314.e4.
This study presents the epidemiological and mycological aspects of 299 patients with nail lesions who were referred to three diagnostic laboratories in the city of Cali. The diagnosis of mycoses was established through visualization of mycotic structures in a direct microscopic examination of skin scrapings and by isolation. Onychomycosis was found in 183 cases (61.2%), of which 141 were in toenails (44 in males and 97 in females), 38 in fingernails (9 males and 29 females), and 4 cases in toenails and fingernails simultaneously (all females). No statistically significant relation was found between sex and onychomycosis. Yeasts accounted for 40.7% of the mycoses, dermatophytes for 38%, nondermatophyte molds for 14% and the etiology was mixed in the remaining cases (7.3%). Candida albicans was the most commonly isolated yeast species; the most common dermatophyte was Trichophyton rubrum and Fusarium spp. and Scytalidium dimidiatum were the most common nondermatophytic molds. Them common fungi found in fingernails were yeasts; in toenails dermatophytes were more prevalent (chi2 with Yates' correction = 19.75, P= 0.000088). Yeasts were observed more frequently in females while dermatophytes were more common in males. The difference between these two etiologic groups was statistically significant (chi2 with Yates' correction = 7.43, P = 0.0064); no relation was observed according to age.
本研究呈现了转诊至卡利市三家诊断实验室的299例甲病变患者的流行病学和真菌学情况。通过对皮肤刮屑进行直接显微镜检查以观察真菌结构并进行分离,从而确诊真菌病。发现183例(61.2%)甲癣患者,其中141例累及趾甲(男性44例,女性97例),38例累及指甲(男性9例,女性29例),4例同时累及趾甲和指甲(均为女性)。未发现性别与甲癣之间存在统计学显著关系。酵母菌占真菌病的40.7%,皮肤癣菌占38%,非皮肤癣菌性霉菌占14%,其余病例病因混合(7.3%)。白色念珠菌是最常分离出的酵母菌种类;最常见的皮肤癣菌是红色毛癣菌,镰刀菌属和半知菌属是最常见的非皮肤癣菌性霉菌。指甲中常见的真菌是酵母菌;趾甲中皮肤癣菌更为普遍(经Yates校正的卡方检验=19.75,P=0.000088)。女性中酵母菌的观察频率更高,而男性中皮肤癣菌更为常见。这两个病因组之间的差异具有统计学显著性(经Yates校正的卡方检验=7.43,P=0.0064);未观察到与年龄的关系。