Schoenbaum Geoffrey, Roesch Matthew
Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn Street, HSF-2 S251, Baltimore, Maryland 21201, USA.
Neuron. 2005 Sep 1;47(5):633-6. doi: 10.1016/j.neuron.2005.07.018.
Orbitofrontal cortex is characterized by its unique pattern of connections with subcortical areas, such as basolateral amygdala. Here we distinguish between the critical role of these areas in associative learning and the pivotal contribution of OFC to the manipulation of this information to control behavior. This contribution reflects the ability of OFC to signal the desirability of expected outcomes, which requires the integration of associative information with information concerning internal states and goals in representational memory.
眶额皮质的特点是与诸如基底外侧杏仁核等皮质下区域有着独特的连接模式。在这里，我们区分了这些区域在联想学习中的关键作用以及眶额皮质对操控此信息以控制行为的关键贡献。这种贡献反映了眶额皮质发出预期结果可取性信号的能力，这需要将联想信息与表征记忆中有关内部状态和目标的信息进行整合。
