Yue Wai-Mun, Brodner Wolfram, Highland Thomas R
Study performed at the Columbia Spine Centre, Columbia, MO, USA.
Spine (Phila Pa 1976). 2005 Oct 1;30(19):2138-44. doi: 10.1097/01.brs.0000180479.63092.17.
A retrospective review.
To determine the clinical and radiologic outcomes beyond 5 years after anterior cervical discectomy and fusion with allograft and plating.
Anterior cervical discectomy and fusion is commonly performed for cervical disc disease. The routine use of allografts and plating, though increasing in popularity, has not been well studied for long-term results and complications.
Seventy-one patients who had anterior cervical discectomy and fusion with allograft and plating an average of 7.2 years prior responded to an invitation to return for a follow-up clinical and radiographic review.
At final review, symptom resolution remained greater than 82% and fusion occurred in 92.6% of the disc spaces operated on. No graft extrusion or migration occurred. Based on our strict criteria, the rates of collapse and subsidence were high, at 47.9% (34 patients) overall. However, in only 6 patients (8.5%) did segmental kyphosis result, none of whom required any revision surgery in the follow-up period. Implant complications occurred in 7 patients (9.9%), none of whom required revision surgeries. Adjacent level degeneration occurred in 52 patients (73.2%). Further cervical spine surgeries were required in 14 patients (19.7%), 2 for inadequate decompression, and 12 for adjacent level disease. Segmental and global cervical lordosis was restored and maintained by the surgery over the study period.
The use of allografts and plate fixation in combination for anterior cervical discectomy and fusion does not compromise the radiologic and clinical outcomes while providing the advantages of donor site morbidity elimination, restoration of cervical segmental lordosis, and not requiring postoperative immobilization.
一项回顾性研究。
确定颈椎前路椎间盘切除、同种异体骨移植融合及钢板固定术后5年以上的临床和影像学结果。
颈椎前路椎间盘切除融合术是治疗颈椎间盘疾病的常用方法。同种异体骨移植和钢板的常规使用虽然越来越普遍,但对其长期效果和并发症尚未进行充分研究。
平均在7.2年前接受颈椎前路椎间盘切除、同种异体骨移植融合及钢板固定术的71例患者应邀返回进行随访临床和影像学检查。
在最终检查时,症状缓解率仍大于82%,手术的椎间盘间隙融合率为92.6%。未发生植骨块挤出或移位。根据我们严格的标准,塌陷和下沉发生率较高,总体为47.9%(34例患者)。然而,仅6例患者(8.5%)出现节段性后凸畸形,在随访期间均无需任何翻修手术。7例患者(9.9%)发生植入物并发症,均无需翻修手术。52例患者(73.2%)出现相邻节段退变。14例患者(19.7%)需要进一步的颈椎手术,2例因减压不充分,12例因相邻节段疾病。在研究期间,手术恢复并维持了节段性和整体颈椎前凸。
颈椎前路椎间盘切除融合术中联合使用同种异体骨移植和钢板固定不会影响影像学和临床结果,同时具有消除供区并发症、恢复颈椎节段前凸以及无需术后制动的优点。